]> http://dumontierlab.com en September 1, 2007 sgd ontology Natalia Villanueva-Rosales UniProt data for yOWL 2.0 UniProt data for yOWL Michel Dumontier rdf/xml true 1997-11-01 2007-11-13 41 CSI1_YEAST YMR5_YEAST Cop9 signalosome-interactor 1 Bowman S. Churcher C.M. Badcock K. Brown D. Chillingworth T. Connor R. Dedman K. Devlin K. Gentles S. Hamlin N. Hunt S. Jagels K. Lye G. Moule S. Odell C. Pearson D. Rajandream M.A. Rice P. Skelton J. Walsh S.V. Whitehead S. Barrell B.G. 1997 Nature 387 90-93 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Wee S. Hetfeld B. Dubiel W. Wolf D.A. doi:10.1186/1471-2156-3-15 2002 BMC Genet. 3 15 FUNCTION OF THE COP9 SIGNALOSOME COMPLEX Maytal-Kivity V. Piran R. Pick E. Hofmann K. Glickman M.H. doi:10.1093/embo-reports/kvf235 2002 EMBO Rep. 3 1215-1221 INTERACTION WITH CSN9 AND CSN12 IDENTIFICATION IN THE COP9 SIGNALOSOME COMPLEX FUNCTION OF THE COP9 SIGNALOSOME COMPLEX Gavin A.-C. Boesche M. Krause R. Grandi P. Marzioch M. Bauer A. Schultz J. Rick J.M. Michon A.-M. Cruciat C.-M. Remor M. Hoefert C. Schelder M. Brajenovic M. Ruffner H. Merino A. Klein K. Hudak M. Dickson D. Rudi T. Gnau V. Bauch A. Bastuck S. Huhse B. Leutwein C. Heurtier M.-A. Copley R.R. Edelmann A. Querfurth E. Rybin V. Drewes G. Raida M. Bouwmeester T. Bork P. Seraphin B. Kuster B. Neubauer G. Superti-Furga G. doi:10.1038/415141a 2002 Nature 415 141-147 INTERACTION WITH RRI1/CSN5 IDENTIFICATION BY MASS SPECTROMETRY Maytal-Kivity V. Pick E. Piran R. Hofmann K. Glickman M.H. doi:10.1016/S1357-2725(02)00378-3 2003 Int. J. Biochem. Cell Biol. 35 706-715 INTERACTION WITH CSN9; CSN12 AND RPN5 IDENTIFICATION IN THE COP9 SIGNALOSOME COMPLEX CSI1 YMR025W YM9711.15 Component of the COP9 signalosome (CSN) complex that is required for cleaving the ubiquitin-like protein RUB1/NEDD8 from neddylated cullin CDC53, a SCF ubiquitin-ligase subunit. The complex is involved in the regulation of the mating pheromone response. Component of the COP9 signalosome (CSN) complex, composed of RRI1/CSN5, CSN9, RRI2/CSN10, PCI8/CSN11, CSN12 and CSI1. In the complex, it probably interacts directly with CSN9 and CSN12. Interacts also with RPN5. Cytoplasm (Probable). Nucleus (Probable). Cop9 signalosome-interactor 1 1 295 false 1 COG2 false 2 CSN12 false 3 CSN9 false 1 RRI1 EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YMR025W KEGG CYGD SGD CSI1 LinkHub GermOnline Saccharomyces cerevisiae SGD IntAct SGD SGD 1997-11-01 1 34520 MDLLKFSSLA ISEINFLHES SFDSIDHSWF LLIGCKLDQD DEIYIPINGN EAESQWYIEK VIRIPMQEND KINQERLERR INLTKVTQKD ICILGILDLC QLEEDENITN KVTEKVLTQL TALALKYLIK YNVFRQHTSF QEAVNSLKGY KIENSVQIGA EIILDFLQDK VQIKDVNDRY QIPTPNNTVD PGFDEFQLID MKDKEINIQK YNNNTIRKLL EKINRMIIFL KNYDATDKPF SSTQDVILRK ISMLVTQLQR GGTSDMNYLL DNKINEIKLL EISCKQWEIS NMLKK true 2006-10-17 2007-11-13 38 YD131_YEAST F-box protein YDR131C Jacq C. Alt-Moerbe J. Andre B. Arnold W. Bahr A. Ballesta J.P.G. Bargues M. Baron L. Becker A. Biteau N. Bloecker H. Blugeon C. Boskovic J. Brandt P. Brueckner M. Buitrago M.J. Coster F. Delaveau T. del Rey F. Dujon B. Eide L.G. Garcia-Cantalejo J.M. Goffeau A. Gomez-Peris A. Granotier C. Hanemann V. Hankeln T. Hoheisel J.D. Jaeger W. Jimenez A. Jonniaux J.-L. Kraemer C. Kuester H. Laamanen P. Legros Y. Louis E.J. Moeller-Rieker S. Monnet A. Moro M. Mueller-Auer S. Nussbaumer B. Paricio N. Paulin L. Perea J. Perez-Alonso M. Perez-Ortin J.E. Pohl T.M. Prydz H. Purnelle B. Rasmussen S.W. Remacha M.A. Revuelta J.L. Rieger M. Salom D. Saluz H.P. Saiz J.E. Saren A.-M. Schaefer M. Scharfe M. Schmidt E.R. Schneider C. Scholler P. Schwarz S. Soler-Mira A. Urrestarazu L.A. Verhasselt P. Vissers S. Voet M. Volckaert G. Wagner G. Wambutt R. Wedler E. Wedler H. Woelfl S. Harris D.E. Bowman S. Brown D. Churcher C.M. Connor R. Dedman K. Gentles S. Hamlin N. Hunt S. Jones L. McDonald S. Murphy L.D. Niblett D. Odell C. Oliver K. Rajandream M.A. Richards C. Shore L. Walsh S.V. Barrell B.G. Dietrich F.S. Mulligan J.T. Allen E. Araujo R. Aviles E. Berno A. Carpenter J. Chen E. Cherry J.M. Chung E. Duncan M. Hunicke-Smith S. Hyman R.W. Komp C. Lashkari D. Lew H. Lin D. Mosedale D. Nakahara K. Namath A. Oefner P. Oh C. Petel F.X. Roberts D. Schramm S. Schroeder M. Shogren T. Shroff N. Winant A. Yelton M.A. Botstein D. Davis R.W. Johnston M. Andrews S. Brinkman R. Cooper J. Ding H. Du Z. Favello A. Fulton L. Gattung S. Greco T. Hallsworth K. Hawkins J. Hillier L.W. Jier M. Johnson D. Johnston L. Kirsten J. Kucaba T. Langston Y. Latreille P. Le T. Mardis E. Menezes S. Miller N. Nhan M. Pauley A. Peluso D. Rifkin L. Riles L. Taich A. Trevaskis E. Vignati D. Wilcox L. Wohldman P. Vaudin M. Wilson R. Waterston R. Albermann K. Hani J. Heumann K. Kleine K. Mewes H.-W. Zollner A. Zaccaria P. 1997 Nature 387 75-78 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Willems A.R. Goh T. Taylor L. Chernushevich I. Shevchenko A. Tyers M. doi:10.1098/rstb.1999.0497 1999 Philos. Trans. R. Soc. Lond., B, Biol. Sci. 354 1533-1550 PROTEIN SEQUENCE OF 132-148 AND 521-529 IDENTIFICATION IN SCF COMPLEX MASS SPECTROMETRY Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Kus B.M. Caldon C.E. Andorn-Broza R. Edwards A.M. doi:10.1002/prot.10620 2004 Proteins 54 455-467 INTERACTION WITH SKP1 YDR131C Part of a SCF E3 ubiquitin ligase complex containing SKP1, CDC53, HRT1 and YDR131C. Vacuole. Contains 1 F-box domain. F-box protein YDR131C 1 556 F-box 1 44 false 1 false 1 SKP1 false 1 YRB2 EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YDR131C KEGG CYGD SGD YDR131C LinkHub GermOnline Saccharomyces cerevisiae InterPro F-box PROSITE FBOX 1 SGD IntAct SGD 1996-11-01 1 65243 MFDKLPYEIF KQIAWRIPQE DKISLTYVCK RSYESIIPFI YQNLFLNETY HINGDYDNSF GTCYWSVLNF HYIDEDDSNT KNDMSNRRLA KVKFSYFERT LAESPKRLCP LINRIRCTWH LNEDVMTNVL KLLSEYGSNL KFVDQFVRSS VNKGLEPLSK QLKTLTLTPP TLMPTHNSVS GSYLNKIDRL LLKCDLSRLE KLSIHINALK YFKNTGSPMK IKALVLNLRP DTLNLAEYDA SDDFLKELEY IDIFDASTLR QLEILSWYSR DDFPSGEEGG FDRLYVKWGL EGFWKFPNIE KLSLASLVYS EFFLMNCLAV FHNLKILKLD YMGKFDFDVS LINFLSKQVC GKKLQRFDIH CQLNHRLFFP MTDNPLTRLN FDGFCPCSTC KNTIHEVILK KIFPETRSKL LKNPNKFQAH NFFYQMFFEN KIMPYTNIID NESPAMGWDS VPIETFVRKF NENLQSTIEN TENITVNKIT REDAISLYHL YLHYLKDVFK VFEQSLPNLE YLTINGIPTK IIQVDELQRC AVPLFYNNGY KSNSVYELVD AEALFS true 2005-11-22 2007-11-13 42 CSN9_YEAST COP9 signalosome complex subunit 9 Jacq C. Alt-Moerbe J. Andre B. Arnold W. Bahr A. Ballesta J.P.G. Bargues M. Baron L. Becker A. Biteau N. Bloecker H. Blugeon C. Boskovic J. Brandt P. Brueckner M. Buitrago M.J. Coster F. Delaveau T. del Rey F. Dujon B. Eide L.G. Garcia-Cantalejo J.M. Goffeau A. Gomez-Peris A. Granotier C. Hanemann V. Hankeln T. Hoheisel J.D. Jaeger W. Jimenez A. Jonniaux J.-L. Kraemer C. Kuester H. Laamanen P. Legros Y. Louis E.J. Moeller-Rieker S. Monnet A. Moro M. Mueller-Auer S. Nussbaumer B. Paricio N. Paulin L. Perea J. Perez-Alonso M. Perez-Ortin J.E. Pohl T.M. Prydz H. Purnelle B. Rasmussen S.W. Remacha M.A. Revuelta J.L. Rieger M. Salom D. Saluz H.P. Saiz J.E. Saren A.-M. Schaefer M. Scharfe M. Schmidt E.R. Schneider C. Scholler P. Schwarz S. Soler-Mira A. Urrestarazu L.A. Verhasselt P. Vissers S. Voet M. Volckaert G. Wagner G. Wambutt R. Wedler E. Wedler H. Woelfl S. Harris D.E. Bowman S. Brown D. Churcher C.M. Connor R. Dedman K. Gentles S. Hamlin N. Hunt S. Jones L. McDonald S. Murphy L.D. Niblett D. Odell C. Oliver K. Rajandream M.A. Richards C. Shore L. Walsh S.V. Barrell B.G. Dietrich F.S. Mulligan J.T. Allen E. Araujo R. Aviles E. Berno A. Carpenter J. Chen E. Cherry J.M. Chung E. Duncan M. Hunicke-Smith S. Hyman R.W. Komp C. Lashkari D. Lew H. Lin D. Mosedale D. Nakahara K. Namath A. Oefner P. Oh C. Petel F.X. Roberts D. Schramm S. Schroeder M. Shogren T. Shroff N. Winant A. Yelton M.A. Botstein D. Davis R.W. Johnston M. Andrews S. Brinkman R. Cooper J. Ding H. Du Z. Favello A. Fulton L. Gattung S. Greco T. Hallsworth K. Hawkins J. Hillier L.W. Jier M. Johnson D. Johnston L. Kirsten J. Kucaba T. Langston Y. Latreille P. Le T. Mardis E. Menezes S. Miller N. Nhan M. Pauley A. Peluso D. Rifkin L. Riles L. Taich A. Trevaskis E. Vignati D. Wilcox L. Wohldman P. Vaudin M. Wilson R. Waterston R. Albermann K. Hani J. Heumann K. Kleine K. Mewes H.-W. Zollner A. Zaccaria P. 1997 Nature 387 75-78 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Wee S. Hetfeld B. Dubiel W. Wolf D.A. doi:10.1186/1471-2156-3-15 2002 BMC Genet. 3 15 FUNCTION OF THE COP9 SIGNALOSOME COMPLEX Maytal-Kivity V. Piran R. Pick E. Hofmann K. Glickman M.H. doi:10.1093/embo-reports/kvf235 2002 EMBO Rep. 3 1215-1221 INTERACTION WITH CSN12 AND CSI1 IDENTIFICATION IN THE COP9 SIGNALOSOME COMPLEX FUNCTION OF THE COP9 SIGNALOSOME COMPLEX Gavin A.-C. Boesche M. Krause R. Grandi P. Marzioch M. Bauer A. Schultz J. Rick J.M. Michon A.-M. Cruciat C.-M. Remor M. Hoefert C. Schelder M. Brajenovic M. Ruffner H. Merino A. Klein K. Hudak M. Dickson D. Rudi T. Gnau V. Bauch A. Bastuck S. Huhse B. Leutwein C. Heurtier M.-A. Copley R.R. Edelmann A. Querfurth E. Rybin V. Drewes G. Raida M. Bouwmeester T. Bork P. Seraphin B. Kuster B. Neubauer G. Superti-Furga G. doi:10.1038/415141a 2002 Nature 415 141-147 INTERACTION WITH RRI1/CSN5 IDENTIFICATION BY MASS SPECTROMETRY Maytal-Kivity V. Pick E. Piran R. Hofmann K. Glickman M.H. doi:10.1016/S1357-2725(02)00378-3 2003 Int. J. Biochem. Cell Biol. 35 706-715 INTERACTION WITH CSN12; CSI1 AND RPN5 IDENTIFICATION IN THE COP9 SIGNALOSOME COMPLEX Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] CSN9 YDR179C Component of the COP9 signalosome (CSN) complex that is required for cleaving the ubiquitin-like protein RUB1/NEDD8 from neddylated cullin CDC53, a SCF ubiquitin-ligase subunit. The complex is involved in the regulation of the mating pheromone response. Component of the COP9 signalosome (CSN) complex, composed of at least RRI1/CSN5, CSN9, RRI2/CSN10, PCI8/CSN11, CSN12 and CSI1. In the complex, it probably interacts directly with CSN12 and CSI1. Interacts also with RPN5. Cytoplasm (Probable). Nucleus (Probable). Present with 358 molecules/cell in log phase SD medium. Contains 1 PCI domain. COP9 signalosome complex subunit 9 1 162 PCI 6 118 false 3 CSI1 false 2 CSN12 false 2 RPN5 EMBL EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YDR179C KEGG CYGD SGD CSN9 LinkHub GermOnline Saccharomyces cerevisiae SGD IntAct SGD SGD 1996-11-01 1 19476 MVMREETIKS LEDPYKYHYK EEWLNTKDPD EQQLFEIFAF GNIKDLPENI ILTSLMRSKL EKLTLVTLSE IYNELSYELI KEECQIEDDG IIESHLIQLQ NIFKAEMDSV SKSMKFSRRF DCRDVYCHEK ELTIIKNPRV TKEYLVQNLR SWETKLKQNI LE true 2005-08-30 2007-10-02 42 CWC21_YEAST Pre-mRNA-splicing factor CWC21 Complexed with CEF1 protein 21 Jacq C. Alt-Moerbe J. Andre B. Arnold W. Bahr A. Ballesta J.P.G. Bargues M. Baron L. Becker A. Biteau N. Bloecker H. Blugeon C. Boskovic J. Brandt P. Brueckner M. Buitrago M.J. Coster F. Delaveau T. del Rey F. Dujon B. Eide L.G. Garcia-Cantalejo J.M. Goffeau A. Gomez-Peris A. Granotier C. Hanemann V. Hankeln T. Hoheisel J.D. Jaeger W. Jimenez A. Jonniaux J.-L. Kraemer C. Kuester H. Laamanen P. Legros Y. Louis E.J. Moeller-Rieker S. Monnet A. Moro M. Mueller-Auer S. Nussbaumer B. Paricio N. Paulin L. Perea J. Perez-Alonso M. Perez-Ortin J.E. Pohl T.M. Prydz H. Purnelle B. Rasmussen S.W. Remacha M.A. Revuelta J.L. Rieger M. Salom D. Saluz H.P. Saiz J.E. Saren A.-M. Schaefer M. Scharfe M. Schmidt E.R. Schneider C. Scholler P. Schwarz S. Soler-Mira A. Urrestarazu L.A. Verhasselt P. Vissers S. Voet M. Volckaert G. Wagner G. Wambutt R. Wedler E. Wedler H. Woelfl S. Harris D.E. Bowman S. Brown D. Churcher C.M. Connor R. Dedman K. Gentles S. Hamlin N. Hunt S. Jones L. McDonald S. Murphy L.D. Niblett D. Odell C. Oliver K. Rajandream M.A. Richards C. Shore L. Walsh S.V. Barrell B.G. Dietrich F.S. Mulligan J.T. Allen E. Araujo R. Aviles E. Berno A. Carpenter J. Chen E. Cherry J.M. Chung E. Duncan M. Hunicke-Smith S. Hyman R.W. Komp C. Lashkari D. Lew H. Lin D. Mosedale D. Nakahara K. Namath A. Oefner P. Oh C. Petel F.X. Roberts D. Schramm S. Schroeder M. Shogren T. Shroff N. Winant A. Yelton M.A. Botstein D. Davis R.W. Johnston M. Andrews S. Brinkman R. Cooper J. Ding H. Du Z. Favello A. Fulton L. Gattung S. Greco T. Hallsworth K. Hawkins J. Hillier L.W. Jier M. Johnson D. Johnston L. Kirsten J. Kucaba T. Langston Y. Latreille P. Le T. Mardis E. Menezes S. Miller N. Nhan M. Pauley A. Peluso D. Rifkin L. Riles L. Taich A. Trevaskis E. Vignati D. Wilcox L. Wohldman P. Vaudin M. Wilson R. Waterston R. Albermann K. Hani J. Heumann K. Kleine K. Mewes H.-W. Zollner A. Zaccaria P. 1997 Nature 387 75-78 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Ohi M.D. Link A.J. Ren L. Jennings J.L. McDonald W.H. Gould K.L. doi:10.1128/MCB.22.7.2011-2024.2002 2002 Mol. Cell. Biol. 22 2011-2024 MASS SPECTROMETRY IDENTIFICATION IN THE CWC COMPLEX Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] CWC21 YDR482C Involved in pre-mRNA splicing. Belongs to the CWC complex, a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the U2, U5 and U6 snRNAs and at least BUD13, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2. Cytoplasm. Nucleus. Present with 556 molecules/cell in log phase SD medium. Belongs to the CWC21 family. Pre-mRNA-splicing factor CWC21 1 135 65 102 false 1 TPD3 EMBL EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YDR482C KEGG CYGD SGD CWC21 LinkHub GermOnline Saccharomyces cerevisiae SGD IntAct 1996-11-01 1 15763 MSYNGIGLKS AKGSSTSGHV QRSLASNNRR RPQGSQQQRQ QRQNAIKKAS HDKASRPLAV QKQIETHMEK REIEVQVSEL RDRLEEEETL SEEQIDKKCE ALRAKLTNEW QEQQRMSSLY TPRKARLTEE QHRHE true 2005-08-30 2007-10-02 50 CWC27_YEAST Peptidyl-prolyl isomerase CWC27 EC 5.2.1.8 Complexed with CEF1 protein 27 Bussey H. Storms R.K. Ahmed A. Albermann K. Allen E. Ansorge W. Araujo R. Aparicio A. Barrell B.G. Badcock K. Benes V. Botstein D. Bowman S. Brueckner M. Carpenter J. Cherry J.M. Chung E. Churcher C.M. Coster F. Davis K. Davis R.W. Dietrich F.S. Delius H. DiPaolo T. Dubois E. Duesterhoeft A. Duncan M. Floeth M. Fortin N. Friesen J.D. Fritz C. Goffeau A. Hall J. Hebling U. Heumann K. Hilbert H. Hillier L.W. Hunicke-Smith S. Hyman R.W. Johnston M. Kalman S. Kleine K. Komp C. Kurdi O. Lashkari D. Lew H. Lin A. Lin D. Louis E.J. Marathe R. Messenguy F. Mewes H.-W. Mirtipati S. Moestl D. Mueller-Auer S. Namath A. Nentwich U. Oefner P. Pearson D. Petel F.X. Pohl T.M. Purnelle B. Rajandream M.A. Rechmann S. Rieger M. Riles L. Roberts D. Schaefer M. Scharfe M. Scherens B. Schramm S. Schroeder M. Sdicu A.-M. Tettelin H. Urrestarazu L.A. Ushinsky S. Vierendeels F. Vissers S. Voss H. Walsh S.V. Wambutt R. Wang Y. Wedler E. Wedler H. Winnett E. Zhong W.-W. Zollner A. Vo D.H. Hani J. 1997 Nature 387 103-105 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Ohi M.D. Link A.J. Ren L. Jennings J.L. McDonald W.H. Gould K.L. doi:10.1128/MCB.22.7.2011-2024.2002 2002 Mol. Cell. Biol. 22 2011-2024 MASS SPECTROMETRY IDENTIFICATION IN THE CWC COMPLEX Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] CWC27 CYP7 YPL064C PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity). Peptidylproline (omega=180) = peptidylproline (omega=0). Belongs to the CWC complex (or PRP19-associated complex), a spliceosome subcomplex composed of the U2, U5 and U6 snRNAs and at least BUD13, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2. Cytoplasm. Nucleus. Present with 2360 molecules/cell in log phase SD medium. Belongs to the cyclophilin-type PPIase family. CWC27 subfamily. Contains 1 PPIase cyclophilin-type domain. Peptidyl-prolyl isomerase CWC27 1 301 PPIase cyclophilin-type 9 159 EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YPL064C KEGG CYGD SGD CWC27 LinkHub GermOnline Saccharomyces cerevisiae InterPro PPIase_cyclophilin Gene3D PPIase_cyclophilin 1 PROSITE CSA_PPIASE_1 true PROSITE CSA_PPIASE_2 true SGD 1996-11-01 1 35026 MSSNIEPQTT AKCILYTTKG NIAIELWAKE CPETCKRFLS MLSDGTFTNG EFKELKPTQW LMFNANSTGE YRTVAEEKNP RIRFNRDGLL GWDRRRNTWF ITVLADSKHV LNDCNVFGKI VGKSIYIFRE ILGGEIEASS RDNDVKRFMY PAVLKDVEIT IPFFEDIFGS KRRLEDNEKK EQEPAKKLVK SAKVKMVYED EQEDDDGDVQ KLKPRKRMIL PAWIKDDSRS EGIKLDASLD QPQEALIREK TELHDNVDEA TTKETESQEN IKEEPMDKRE RETLAMLSKF QERIKNKNIL K true 1993-07-01 2007-11-13 68 BET4_YEAST MAD2_YEAST Geranylgeranyl transferase type-2 subunit alpha EC 2.5.1.60 Geranylgeranyl transferase type II subunit alpha Type II protein geranyl-geranyltransferase subunit alpha GGTase-II-alpha PGGT YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha Li R. Murray A.W. doi:10.1016/0092-8674(81)90015-5 1991 Cell 66 519-531 NUCLEOTIDE SEQUENCE [GENOMIC DNA] Li R. Chen R.-H. Murray A.W. 1994-08 EMBL/GenBank/DDBJ SEQUENCE REVISION TO 171 Galibert F. Alexandraki D. Baur A. Boles E. Chalwatzis N. Chuat J.-C. Coster F. Cziepluch C. de Haan M. Domdey H. Durand P. Entian K.-D. Gatius M. Goffeau A. Grivell L.A. Hennemann A. Herbert C.J. Heumann K. Hilger F. Hollenberg C.P. Huang M.-E. Jacq C. Jauniaux J.-C. Katsoulou C. Kirchrath L. Kleine K. Kordes E. Koetter P. Liebl S. Louis E.J. Manus V. Mewes H.-W. Miosga T. Obermaier B. Perea J. Pohl T.M. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rasmussen S.W. Rose M. Rossau R. Schaaff-Gerstenschlaeger I. Smits P.H.M. Scarcez T. Soriano N. To Van D. Tzermia M. Van Broekhoven A. Vandenbol M. Wedler H. von Wettstein D. Wambutt R. Zagulski M. Zollner A. Karpfinger-Hartl L. 1996 EMBO J. 15 2031-2049 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Brachat S. Dietrich F.S. Voegeli S. Zhang Z. Stuart L. Lerch A. Gates K. Gaffney T.D. Philippsen P. doi:10.1186/gb-2003-4-7-r45 2003 Genome Biol. 4 RESEARCH45.1-RESEARCH45.13 REVISION OF GENE MODEL ATCC 204511 / S288c / AB972 Li R. Havel C. Watson J.A. Murray A.W. doi:10.1038/366082a0 1993 Nature 366 82-84 Li R. Havel C. Watson J.A. Murray A.W. 1994 Nature 371 438 CHARACTERIZATION Jiang Y. Rossi G. Ferro-Novick S. doi:10.1038/366084a0 1993 Nature 366 84-86 CHARACTERIZATION BET4 YJL031C J1254 Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both cysteines may become modified. Acts on YPT1 and SEC4. Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. Heterodimer of an alpha and a beta subunit. Belongs to the protein prenyltransferase subunit alpha family. Contains 5 PFTA repeats. Was originally (#{citation 1}) thought to be MAD2. Geranylgeranyl transferase type-2 subunit alpha 1 327 PFTA 1 44 78 PFTA 2 84 118 PFTA 3 123 157 PFTA 4 163 197 PFTA 5 207 241 false 1 BET2 EMBL Sequence problems. EMBL Sequence problems. PIR RefSeq HSSP 1LTX DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YJL031C KEGG CYGD SGD BET4 LinkHub GermOnline Saccharomyces cerevisiae InterPro Prenyl_trans InterPro Prenyl_trans_a Gene3D Prenyl_trans 1 Pfam PPTA 5 PROSITE PFTA 5 SGD IntAct SGD SGD 2005-08-30 3 39675 MHGIKRKQWT KELLRQKRVQ DEKKIYDYRS LTENVLNMRD EKIYSIEALK KTSELLEKNP EFNAIWNYRR DIIASLASEL EIPFWDKELV FVMMLLKDYP KVYWIWNHRL WVLKHYPTSS PKVWQTELAV VNKLLEQDAR NYHGWHYRRI VVGNIESITN KSLDKEEFEY TTIKINNNIS NYSAWHQRVQ IISRMFQKGE VGNQKEYIRT EISYIINAMF TDAEDQSVWF YIKWFIKNDI VCKTLDEQEY LKMLKDLREN ILLINNDEIE FSGKQNIWCL KILLVLEDIL EEKEALTERS SEQYLVQLID ADPLRKNRYL HLLEQHK true 1996-10-01 2007-11-13 49 COG6_YEAST YNE1_YEAST COD2_YEAST Conserved oligomeric Golgi complex subunit 6 COG complex subunit 6 Complexed with DOR1 protein 2 Protein SEC37 Philippsen P. Kleine K. Poehlmann R. Duesterhoeft A. Hamberg K. Hegemann J.H. Obermaier B. Urrestarazu L.A. Aert R. Albermann K. Altmann R. Andre B. Baladron V. Ballesta J.P.G. Becam A.-M. Beinhauer J.D. Boskovic J. Buitrago M.J. Bussereau F. Coster F. Crouzet M. D'Angelo M. Dal Pero F. De Antoni A. del Rey F. Doignon F. Domdey H. Dubois E. Fiedler T.A. Fleig U. Floeth M. Fritz C. Gaillardin C. Garcia-Cantalejo J.M. Glansdorff N. Goffeau A. Gueldener U. Herbert C.J. Heumann K. Heuss-Neitzel D. Hilbert H. Hinni K. Iraqui Houssaini I. Jacquet M. Jimenez A. Jonniaux J.-L. Karpfinger-Hartl L. Lanfranchi G. Lepingle A. Levesque H. Lyck R. Maftahi M. Mallet L. Maurer C.T.C. Messenguy F. Mewes H.-W. Moestl D. Nasr F. Nicaud J.-M. Niedenthal R.K. Pandolfo D. Pierard A. Piravandi E. Planta R.J. Pohl T.M. Purnelle B. Rebischung C. Remacha M.A. Revuelta J.L. Rinke M. Saiz J.E. Sartorello F. Scherens B. Sen-Gupta M. Soler-Mira A. Urbanus J.H.M. Valle G. Van Dyck L. Verhasselt P. Vierendeels F. Vissers S. Voet M. Volckaert G. Wach A. Wambutt R. Wedler H. Zollner A. Hani J. 1997 Nature 387 93-98 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Whyte J.R. Munro S. doi:10.1016/S1534-5807(01)00063-6 2001 Dev. Cell 1 527-537 SUBUNIT Suvorova E.S. Duden R. Lupashin V.V. doi:10.1083/jcb.200111081 2002 J. Cell Biol. 157 631-643 IDENTIFICATION IN THE COG COMPLEX FUNCTION OF THE COG COMPLEX Ram R.J. Li B. Kaiser C.A. doi:10.1091/mbc.01-10-0495 2002 Mol. Biol. Cell 13 1484-1500 FUNCTION IDENTIFICATION IN THE COG COMPLEX Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Loh E. Hong W. doi:10.1074/jbc.M400662200 2004 J. Biol. Chem. 279 24640-24648 COMPOSITION OF THE COG COMPLEX INTERACTION WITH COG3 AND COG4 COG6 COD2 SEC37 TFI2 YNL041C N2675 Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. Component of the conserved oligomeric Golgi (COG or Sec34/Sec35) complex which consists of eight different proteins COG1-COG8. Golgi apparatus membrane; Peripheral membrane protein (By similarity). Present with 1720 molecules/cell in log phase SD medium. Belongs to the COG6 family. Conserved oligomeric Golgi complex subunit 6 1 839 false 1 IVY1 false 1 NUP49 false 1 SNX4 false 1 VAC14 EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YNL041C KEGG CYGD SGD COG6 LinkHub GermOnline Saccharomyces cerevisiae InterPro COG6 PANTHER COG6 1 Pfam COG6 1 SGD IntAct SGD 1996-10-01 1 96976 MDFVVDYQTY AMADTATPEL PEPEPRLNLT SDAQSQPTGK LDLQFKLPDL QRYSNNNATL PVDNDGAGSK DLHKKMTHYA MSSIDKIQLS NPSKQLGQNS QDEKLSQQES QNFTNYEPKN LDLSKLVSPS SGSNKNTTNL VLSNKLSKIL NNYTLINYQA TVQLRKSLKV LEENKERLSL DEQKLMNPEY VGTLARRALR TDLESQLLKE HITVLEEFKP IIRRIKRLSS SVEKIQRTSE KLLSNETNEV PTNNVVLQEI DQYRLKAEQL KLKKKILLSI RDRFTLNQVE DDVITNGTID NIFFEVVKKV INIKDESSFL LTLPNLNAGN ALIMGVNEIL EKTNKKIFNY LIDFLYSFES SSNLLNDHGT TEQESLNIFR KSLVFLSSDL ELFNELLKRV TTLRSKSILD EFLSQFDMNS TTSKPIILSA HDPIRYIGDV LASVHSIIAN EADFVKSLFD FQDEDLKDTP ISILQQNKTF LKGIDNKLLN DIIQSLSNSC RIRIEQIVRF EENPIINFEI VRLLKLYRVM FERKGIQDDS SIINNLKSLE DISKNRIIGY YEDYMKQTVM AETKNSSDDL LPPEWLSEYM NKLVELFEIY EKTHAAEDEE SEDNKLLSSK NLQTIVEQPI KDVLLKQLQT SFPLAKKNEK EKASLLTIEI NCFDLIKSRL QPFEGLFAQD DDSRKITIWV CDKLKEYTKQ MLTLQIKFLF ENTGLDLYSN LVNMIFPVDS VKDELDYDMY LALRDNSLME LDMVRKNVHD KLNYYLPQAL TDVQGNLLFK LTSPMIADEI CDECFKKLSL FYNIFRKLLI HLYPNKKDQV FEILNFSTDE FDMLIGIDH true 1996-10-01 2007-10-02 57 TEX1_YEAST YNZ3_YEAST Protein TEX1 Trex component 1 Sen-Gupta M. Gueldener U. Beinhauer J.D. Fiedler T.A. Hegemann J.H. doi:10.1002/(SICI)1097-0061(199707)13:9<849::AID-YEA106>3.3.CO;2-E 1997 Yeast 13 849-860 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 96604 / S288c / FY1679 Philippsen P. Kleine K. Poehlmann R. Duesterhoeft A. Hamberg K. Hegemann J.H. Obermaier B. Urrestarazu L.A. Aert R. Albermann K. Altmann R. Andre B. Baladron V. Ballesta J.P.G. Becam A.-M. Beinhauer J.D. Boskovic J. Buitrago M.J. Bussereau F. Coster F. Crouzet M. D'Angelo M. Dal Pero F. De Antoni A. del Rey F. Doignon F. Domdey H. Dubois E. Fiedler T.A. Fleig U. Floeth M. Fritz C. Gaillardin C. Garcia-Cantalejo J.M. Glansdorff N. Goffeau A. Gueldener U. Herbert C.J. Heumann K. Heuss-Neitzel D. Hilbert H. Hinni K. Iraqui Houssaini I. Jacquet M. Jimenez A. Jonniaux J.-L. Karpfinger-Hartl L. Lanfranchi G. Lepingle A. Levesque H. Lyck R. Maftahi M. Mallet L. Maurer C.T.C. Messenguy F. Mewes H.-W. Moestl D. Nasr F. Nicaud J.-M. Niedenthal R.K. Pandolfo D. Pierard A. Piravandi E. Planta R.J. Pohl T.M. Purnelle B. Rebischung C. Remacha M.A. Revuelta J.L. Rinke M. Saiz J.E. Sartorello F. Scherens B. Sen-Gupta M. Soler-Mira A. Urbanus J.H.M. Valle G. Van Dyck L. Verhasselt P. Vierendeels F. Vissers S. Voet M. Volckaert G. Wach A. Wambutt R. Wedler H. Zollner A. Hani J. 1997 Nature 387 93-98 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Straesser K. Masuda S. Mason P. Pfannstiel J. Oppizzi M. Rodriguez-Navarro S. Rondon A.G. Aguilera A. Struhl K. Reed R. Hurt E. doi:10.1038/nature746 2002 Nature 417 304-308 IDENTIFICATION IN TREX COMPLEX MASS SPECTROMETRY TEX1 YNL253W N0860 Component the TREX complex, which operates in coupling transcription elongation to mRNA export. Component of the transcription/export (TREX) complex, which is at least is formed of SUB2, TEX1 and YRA1 and the THO complex composed of HPR1, MFT1, RLR1 and THP1. Nucleus (Probable). Contains 5 WD repeats. Protein TEX1 1 422 WD 1 61 100 WD 2 158 197 WD 3 207 246 WD 4 251 290 WD 5 293 332 EMBL EMBL EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YNL253W KEGG CYGD SGD TEX1 LinkHub GermOnline Saccharomyces cerevisiae InterPro WD40 Pfam WD40 1 SMART WD40 5 PROSITE WD_REPEATS_1 true PROSITE WD_REPEATS_2 1 PROSITE WD_REPEATS_REGION 1 SGD SGD 1996-10-01 1 47167 MSTIGAVDIL NQKTITSEVA ASVTSKYLQS TFSKGNTSHI EDKRFIHVSS RSHSRFTSTP ITPNEILSLK FHVSGSSMAY SRMDGSLTVW FIKDASFDKS VEVYIPDCCG SDKLATDLSW NPTSLNQIAV VSNSSEISLL LINEKSLTAS KLRTLSLGSK TKVNTCLYDP LGNWLLAATK SEKIYLFDVK KDHSSVCSLN ISDISQEDND VVYSLAWSNG GSHIFIGFKS GYLAILKAKH GILEVCTKIK AHTGPITEIK MDPWGRNFIT GSIDGNCYVW NMKSLCCELI INDLNSAVTT LDVCHLGKIL GICTEDEMVY FYDLNSGNLL HSKSLANYKT DPVLKFYPDK SWYIMSGKND TLSNHFVKNE KNLITYWKDM FDNTMIEKRR KNNGGGNNHN KRTSKNTDRI GKDRPSRFNS KK true 1996-10-01 2007-10-02 50 CWC25_YEAST YNY5_YEAST Pre-mRNA-splicing factor CWC25 Complexed with CEF1 protein 25 Sen-Gupta M. Gueldener U. Beinhauer J.D. Fiedler T.A. Hegemann J.H. doi:10.1002/(SICI)1097-0061(199707)13:9<849::AID-YEA106>3.3.CO;2-E 1997 Yeast 13 849-860 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Philippsen P. Kleine K. Poehlmann R. Duesterhoeft A. Hamberg K. Hegemann J.H. Obermaier B. Urrestarazu L.A. Aert R. Albermann K. Altmann R. Andre B. Baladron V. Ballesta J.P.G. Becam A.-M. Beinhauer J.D. Boskovic J. Buitrago M.J. Bussereau F. Coster F. Crouzet M. D'Angelo M. Dal Pero F. De Antoni A. del Rey F. Doignon F. Domdey H. Dubois E. Fiedler T.A. Fleig U. Floeth M. Fritz C. Gaillardin C. Garcia-Cantalejo J.M. Glansdorff N. Goffeau A. Gueldener U. Herbert C.J. Heumann K. Heuss-Neitzel D. Hilbert H. Hinni K. Iraqui Houssaini I. Jacquet M. Jimenez A. Jonniaux J.-L. Karpfinger-Hartl L. Lanfranchi G. Lepingle A. Levesque H. Lyck R. Maftahi M. Mallet L. Maurer C.T.C. Messenguy F. Mewes H.-W. Moestl D. Nasr F. Nicaud J.-M. Niedenthal R.K. Pandolfo D. Pierard A. Piravandi E. Planta R.J. Pohl T.M. Purnelle B. Rebischung C. Remacha M.A. Revuelta J.L. Rinke M. Saiz J.E. Sartorello F. Scherens B. Sen-Gupta M. Soler-Mira A. Urbanus J.H.M. Valle G. Van Dyck L. Verhasselt P. Vierendeels F. Vissers S. Voet M. Volckaert G. Wach A. Wambutt R. Wedler H. Zollner A. Hani J. 1997 Nature 387 93-98 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Ohi M.D. Link A.J. Ren L. Jennings J.L. McDonald W.H. Gould K.L. doi:10.1128/MCB.22.7.2011-2024.2002 2002 Mol. Cell. Biol. 22 2011-2024 MASS SPECTROMETRY IDENTIFICATION IN THE CWC COMPLEX Hazbun T.R. Malmstroem L. Anderson S. Graczyk B.J. Fox B. Riffle M. Sundin B.A. Aranda J.D. McDonald W.H. Chiu C.-H. Snydsman B.E. Bradley P. Muller E.G.D. Fields S. Baker D. Yates J.R. III Davis T.N. doi:10.1016/S1097-2765(03)00476-3 2003 Mol. Cell 12 1353-1365 FUNCTION MASS SPECTROMETRY INTERACTION WITH CLF1; PRP8; PRP19 AND SNU114 SUBCELLULAR LOCATION Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] CWC25 YNL245C N0901 Involved in pre-mRNA splicing. Belongs to the CWC complex, a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the U2, U5 and U6 snRNAs and at least BUD13, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2. Interacts with CLF1, PRP8, PRP19 and SNU114. Nucleus. Present with 861 molecules/cell in log phase SD medium. Belongs to the CWC25 family. Pre-mRNA-splicing factor CWC25 1 179 25 57 EMBL EMBL EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YNL245C KEGG CYGD SGD CWC25 LinkHub GermOnline Saccharomyces cerevisiae SGD SGD 1996-10-01 1 20374 MGSGDLNLLK SWNPKLMKNR KKVWETEQDL ITEQQKLNTR LKEIEKEREL NELLNESSKD KPETLKNDLA LKKSGLEWMY QDAKLSDEKE DYLLGKKKLD SSILNQPATP PVRAATTISA SGAATSISSQ KKKSKLLKDD PMSKFKVTKQ QRRTPDSTKK RAMSQRGKPL SKPAPDLDY true 1996-10-01 2007-11-13 52 ELOA1_YEAST YNX0_YEAST Elongin-A Pandolfo D. de Antoni A. Lanfranchi G. Valle G. doi:10.1002/(SICI)1097-0061(199609)12:10B<1071::AID-YEA4>3.3.CO;2-J 1996 Yeast 12 1071-1076 NUCLEOTIDE SEQUENCE [GENOMIC DNA] Philippsen P. Kleine K. Poehlmann R. Duesterhoeft A. Hamberg K. Hegemann J.H. Obermaier B. Urrestarazu L.A. Aert R. Albermann K. Altmann R. Andre B. Baladron V. Ballesta J.P.G. Becam A.-M. Beinhauer J.D. Boskovic J. Buitrago M.J. Bussereau F. Coster F. Crouzet M. D'Angelo M. Dal Pero F. De Antoni A. del Rey F. Doignon F. Domdey H. Dubois E. Fiedler T.A. Fleig U. Floeth M. Fritz C. Gaillardin C. Garcia-Cantalejo J.M. Glansdorff N. Goffeau A. Gueldener U. Herbert C.J. Heumann K. Heuss-Neitzel D. Hilbert H. Hinni K. Iraqui Houssaini I. Jacquet M. Jimenez A. Jonniaux J.-L. Karpfinger-Hartl L. Lanfranchi G. Lepingle A. Levesque H. Lyck R. Maftahi M. Mallet L. Maurer C.T.C. Messenguy F. Mewes H.-W. Moestl D. Nasr F. Nicaud J.-M. Niedenthal R.K. Pandolfo D. Pierard A. Piravandi E. Planta R.J. Pohl T.M. Purnelle B. Rebischung C. Remacha M.A. Revuelta J.L. Rinke M. Saiz J.E. Sartorello F. Scherens B. Sen-Gupta M. Soler-Mira A. Urbanus J.H.M. Valle G. Van Dyck L. Verhasselt P. Vierendeels F. Vissers S. Voet M. Volckaert G. Wach A. Wambutt R. Wedler H. Zollner A. Hani J. 1997 Nature 387 93-98 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Botuyan M.V. Koth C.M. Mer G. Chakrabartty A. Conaway J.W. Conaway R.C. Edwards A.M. Arrowsmith C.H. Chazin W.J. doi:10.1073/pnas.96.16.9033 1999 Proc. Natl. Acad. Sci. U.S.A. 96 9033-9038 INTERACTION WITH ELC1 Koth C.M. Botuyan M.V. Moreland R.J. Jansma D.B. Conaway J.W. Conaway R.C. Chazin W.J. Friesen J.D. Arrowsmith C.H. Edwards A.M. doi:10.1074/jbc.275.15.11174 2000 J. Biol. Chem. 275 11174-11180 IDENTIFICATION OF THE ELA1-ELC1 COMPLEX Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Chi A. Huttenhower C. Geer L.Y. Coon J.J. Syka J.E.P. Bai D.L. Shabanowitz J. Burke D.J. Troyanskaya O.G. Hunt D.F. doi:10.1073/pnas.0607084104 2007 Proc. Natl. Acad. Sci. U.S.A. 104 2193-2198 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-278 MASS SPECTROMETRY ELA1 YNL230C N1161 Forms a complex with SKP1-like protein ELC1. Present with 815 molecules/cell in log phase SD medium. In contrast to other members of the family it does not integrate a functional E3 ubiquitin complex. Belongs to the ELA1 family. Contains 1 F-box domain. Elongin-A 1 379 F-box 19 63 ELC1-binding 1 143 Phosphoserine 278 278 false 1 HAT1 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YNL230C KEGG CYGD SGD ELA1 LinkHub GermOnline Saccharomyces cerevisiae InterPro F-box InterPro RNA_pol_II_trans_fac_SIII_A Pfam Elongin_A 1 PROSITE FBOX 1 SGD IntAct SGD 1996-10-01 1 43981 MKSLQTLCEI SLMRNHSNIQ SVSNVPYHLL KRILQKVKIP QLLKLEKSNV LLIFDDDELW LEFLRQDFPT NVHEQFVSKR DIICKYYFDF VKENDIELYH SNQDLLKSCV RQSVVKDIRN NKYRIPYRML YSKYQQEVEK KQEESAERLR LEMQKLQQER EKKQTIVVDH TVYFKKRNTK KTTRLHNEPH SQLYMKSLKD HESRLKHFKD GGFNIAKRHA QRVAFGGQAG GQSSSPKKGP LSIKPEPVKV NRQMDNVTAE KKDVTQPITP VKKRRSESPS IFLNRKKPAL FRPTPKTNAA GSRPHTTAIT NDHRTTSHPY PHKDVVTSIS SVTANPVTKG HKKKKSGIFV RNAGSDGDSF PHVTATGPTT RPYIYEPRK true 1996-10-01 2007-10-02 45 RM50_YEAST YN8C_YEAST Mitochondrial 54S ribosomal protein L50 Philippsen P. Kleine K. Poehlmann R. Duesterhoeft A. Hamberg K. Hegemann J.H. Obermaier B. Urrestarazu L.A. Aert R. Albermann K. Altmann R. Andre B. Baladron V. Ballesta J.P.G. Becam A.-M. Beinhauer J.D. Boskovic J. Buitrago M.J. Bussereau F. Coster F. Crouzet M. D'Angelo M. Dal Pero F. De Antoni A. del Rey F. Doignon F. Domdey H. Dubois E. Fiedler T.A. Fleig U. Floeth M. Fritz C. Gaillardin C. Garcia-Cantalejo J.M. Glansdorff N. Goffeau A. Gueldener U. Herbert C.J. Heumann K. Heuss-Neitzel D. Hilbert H. Hinni K. Iraqui Houssaini I. Jacquet M. Jimenez A. Jonniaux J.-L. Karpfinger-Hartl L. Lanfranchi G. Lepingle A. Levesque H. Lyck R. Maftahi M. Mallet L. Maurer C.T.C. Messenguy F. Mewes H.-W. Moestl D. Nasr F. Nicaud J.-M. Niedenthal R.K. Pandolfo D. Pierard A. Piravandi E. Planta R.J. Pohl T.M. Purnelle B. Rebischung C. Remacha M.A. Revuelta J.L. Rinke M. Saiz J.E. Sartorello F. Scherens B. Sen-Gupta M. Soler-Mira A. Urbanus J.H.M. Valle G. Van Dyck L. Verhasselt P. Vierendeels F. Vissers S. Voet M. Volckaert G. Wach A. Wambutt R. Wedler H. Zollner A. Hani J. 1997 Nature 387 93-98 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Gan X. Kitakawa M. Yoshino K. Oshiro N. Yonezawa K. Isono K. 2002 Eur. J. Biochem. 269 5203-5214 IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL LARGE COMPLEX MASS SPECTROMETRY Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Reinders J. Zahedi R.P. Pfanner N. Meisinger C. Sickmann A. doi:10.1021/pr050477f 2006 J. Proteome Res. 5 1543-1554 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] MASS SPECTROMETRY MRPL50 YNR022C N3220 Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S). Mitochondrion. Mitochondrial 54S ribosomal protein L50 1 139 EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YNR022C KEGG CYGD SGD MRPL50 LinkHub GermOnline Saccharomyces cerevisiae SGD SGD SGD 1996-10-01 1 16283 MLHCTQVCLS ALTKRTHRVK VQVLKDFPRF QLYKGQVANV KPSLMRNYLH NFNGAKYILS EEHDINTELL KQYQTLEAKL EEDHQQLSKR HETEVQKNME LRKESVFGHK KEEKPKEEKK GLLDSGITIE EVKIPGLDI true 1996-10-01 2007-11-13 59 CWC24_YEAST YL23_YEAST Pre-mRNA-splicing factor CWC24 Complexed with CEF1 protein 24 Johnston M. Hillier L.W. Riles L. Albermann K. Andre B. Ansorge W. Benes V. Brueckner M. Delius H. Dubois E. Duesterhoeft A. Entian K.-D. Floeth M. Goffeau A. Hebling U. Heumann K. Heuss-Neitzel D. Hilbert H. Hilger F. Kleine K. Koetter P. Louis E.J. Messenguy F. Mewes H.-W. Miosga T. Moestl D. Mueller-Auer S. Nentwich U. Obermaier B. Piravandi E. Pohl T.M. Portetelle D. Purnelle B. Rechmann S. Rieger M. Rinke M. Rose M. Scharfe M. Scherens B. Scholler P. Schwager C. Schwarz S. Underwood A.P. Urrestarazu L.A. Vandenbol M. Verhasselt P. Vierendeels F. Voet M. Volckaert G. Voss H. Wambutt R. Wedler E. Wedler H. Zimmermann F.K. Zollner A. Hani J. Hoheisel J.D. 1997 Nature 387 87-90 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Ohi M.D. Link A.J. Ren L. Jennings J.L. McDonald W.H. Gould K.L. doi:10.1128/MCB.22.7.2011-2024.2002 2002 Mol. Cell. Biol. 22 2011-2024 MASS SPECTROMETRY IDENTIFICATION IN THE CWC COMPLEX Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Gruhler A. Olsen J.V. Mohammed S. Mortensen P. Faergeman N.J. Mann M. Jensen O.N. doi:10.1074/mcp.M400219-MCP200 2005 Mol. Cell. Proteomics 4 310-327 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-33 MASS SPECTROMETRY Li X. Gerber S.A. Rudner A.D. Beausoleil S.A. Haas W. Villen J. Elias J.E. Gygi S.P. doi:10.1021/pr060559j 2007 J. Proteome Res. 6 1190-1197 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-33 MASS SPECTROMETRY Chi A. Huttenhower C. Geer L.Y. Coon J.J. Syka J.E.P. Bai D.L. Shabanowitz J. Burke D.J. Troyanskaya O.G. Hunt D.F. doi:10.1073/pnas.0607084104 2007 Proc. Natl. Acad. Sci. U.S.A. 104 2193-2198 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-105 MASS SPECTROMETRY CWC24 YLR323C L8543.3 Involved in pre-mRNA splicing. Belongs to the CWC complex, a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the U2, U5 and U6 snRNAs and at least BUD13, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2. Nucleus. Present with 996 molecules/cell in log phase SD medium. Belongs to the CWC24 family. Contains 1 C3H1-type zinc finger. Contains 1 RING-type zinc finger. Pre-mRNA-splicing factor CWC24 1 259 C3H1-type 144 163 RING-type 199 237 Phosphoserine 33 33 Phosphoserine 105 105 EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YLR323C KEGG CYGD SGD CWC24 LinkHub GermOnline Saccharomyces cerevisiae InterPro Znf_CCCH InterPro Znf_RING Pfam zf-C3HC4 1 Pfam zf-CCCH 1 SMART RING 1 SMART ZnF_C3H1 1 PROSITE ZF_RING_1 true PROSITE ZF_RING_2 1 SGD 1996-10-01 1 29741 MFRKRLVNKS SSDEKNQKKR QKINFSEEKL VASDEEKGSS DLMSLAKSGN SRTLQLSHEN EGKLQKKGED LDKYTLTVND DSTKEDLLNF ERKELAEKAK KRRPSDDNEL VLNMSGKNKR LTKQINQPTN IRTTVLMDFQ PDVCKDYKQT GYCGYGDSCK FLHSRDDFKT GWKLNQEWNA DKEDSKAVTL DLEKIPFKCT LCKEDYKSPV VTNCGHYFCG SCFAKDMKKG TKCFICHKET HGSAKVASDL QKMLNKRKS true 1996-10-01 2007-11-13 49 CWC22_YEAST YG5U_YEAST Pre-mRNA-splicing factor CWC22 Complexed with CEF1 protein 22 Volckaert G. Voet M. Robben J. doi:10.1002/(SICI)1097-0061(19970315)13:3<251::AID-YEA63>3.3.CO;2-I 1997 Yeast 13 251-259 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Tettelin H. Agostoni-Carbone M.L. Albermann K. Albers M. Arroyo J. Backes U. Barreiros T. Bertani I. Bjourson A.J. Brueckner M. Bruschi C.V. Carignani G. Castagnoli L. Cerdan E. Clemente M.L. Coblenz A. Coglievina M. Coissac E. Defoor E. Del Bino S. Delius H. Delneri D. de Wergifosse P. Dujon B. Durand P. Entian K.-D. Eraso P. Escribano V. Fabiani L. Fartmann B. Feroli F. Feuermann M. Frontali L. Garcia-Gonzalez M. Garcia-Saez M.I. Goffeau A. Guerreiro P. Hani J. Hansen M. Hebling U. Hernandez K. Heumann K. Hilger F. Hofmann B. Indge K.J. James C.M. Klima R. Koetter P. Kramer B. Kramer W. Lauquin G. Leuther H. Louis E.J. Maillier E. Marconi A. Martegani E. Mazon M.J. Mazzoni C. McReynolds A.D.K. Melchioretto P. Mewes H.-W. Minenkova O. Mueller-Auer S. Nawrocki A. Netter P. Neu R. Nombela C. Oliver S.G. Panzeri L. Paoluzi S. Plevani P. Portetelle D. Portillo F. Potier S. Purnelle B. Rieger M. Riles L. Rinaldi T. Robben J. Rodrigues-Pousada C. Rodriguez-Belmonte E. Rodriguez-Torres A.M. Rose M. Ruzzi M. Saliola M. Sanchez-Perez M. Schaefer B. Schaefer M. Scharfe M. Schmidheini T. Schreer A. Skala J. Souciet J.-L. Steensma H.Y. Talla E. Thierry A. Vandenbol M. van der Aart Q.J.M. Van Dyck L. Vanoni M. Verhasselt P. Voet M. Volckaert G. Wambutt R. Watson M.D. Weber N. Wedler E. Wedler H. Wipfli P. Wolf K. Wright L.F. Zaccaria P. Zimmermann M. Zollner A. Kleine K. 1997 Nature 387 81-84 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Ohi M.D. Link A.J. Ren L. Jennings J.L. McDonald W.H. Gould K.L. doi:10.1128/MCB.22.7.2011-2024.2002 2002 Mol. Cell. Biol. 22 2011-2024 MASS SPECTROMETRY IDENTIFICATION IN THE CWC COMPLEX Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Smolka M.B. Albuquerque C.P. Chen S.H. Zhou H. doi:10.1073/pnas.0701622104 2007 Proc. Natl. Acad. Sci. U.S.A. 104 10364-10369 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-540 MASS SPECTROMETRY CWC22 YGR278W May be involved in pre-mRNA splicing. Belongs to the CWC complex (or PRP19-associated complex), a spliceosome subcomplex composed of the U2, U5 and U6 snRNAs and at least BUD13, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2. Cytoplasm. Nucleus. Present with 3260 molecules/cell in log phase SD medium. Belongs to the CWC22 family. Contains 1 MA3 domain. Contains 1 MIF4G domain. Pre-mRNA-splicing factor CWC22 1 577 MIF4G 22 204 MA3 291 398 Arg-rich 533 577 Phosphoserine 540 540 EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YGR278W KEGG CYGD SGD CWC22 LinkHub GermOnline Saccharomyces cerevisiae InterPro IF_eIF4G_MA3 InterPro MIF4G-like_typ-3 Pfam MA3 1 Pfam MIF4G 1 SMART MA3 1 SMART MIF4G 1 SGD SGD 1996-10-01 1 67294 MSTATIQDED IKFQRENWEM IRSHVSPIIS NLTMDNLQES HRDLFQVNIL IGRNIICKNV VDFTLNKQNG RLIPALSALI ALLNSDIPDI GETLAKELML MFVQQFNRKD YVSCGNILQC LSILFLYDVI HEIVILQILL LLLEKNSLRL VIAVMKICGW KLALVSKKTH DMIWEKLRYI LQTQELSSTL RESLETLFEI RQKDYKSGSQ GLFILDPTSY TVHTHSYIVS DEDEANKELG NFEKCENFNE LTMAFDTLRQ KLLINNTSDT NEGSNSQLQI YDMTSTNDVE FKKKIYLVLK SSLSGDEAAH KLLKLKIANN LKKSVVDIII KSSLQESTFS KFYSILSERM ITFHRSWQTA YNETFEQNYT QDIEDYETDQ LRILGKFWGH LISYEFLPMD CLKIIKLTEE ESCPQGRIFI KFLFQELVNE LGLDELQLRL NSSKLDGMFP LEGDAEHIRY SINFFTAIGL GLLTEDMRSR LTIIQEVEDA EEEEKKLREE EELEKLRKKA RESQPTQGPK IHESRLFLQK DTRENSRSRS PFTVETRKRA RSRTPPRGSR NHRNRSRTPP ARRQRHR true 1996-10-01 2007-12-04 47 COG7_YEAST YGA5_YEAST COD5_YEAST Conserved oligomeric Golgi complex subunit 7 COG complex subunit 7 Complexed with DOR1 protein 5 Tettelin H. Agostoni-Carbone M.L. Albermann K. Albers M. Arroyo J. Backes U. Barreiros T. Bertani I. Bjourson A.J. Brueckner M. Bruschi C.V. Carignani G. Castagnoli L. Cerdan E. Clemente M.L. Coblenz A. Coglievina M. Coissac E. Defoor E. Del Bino S. Delius H. Delneri D. de Wergifosse P. Dujon B. Durand P. Entian K.-D. Eraso P. Escribano V. Fabiani L. Fartmann B. Feroli F. Feuermann M. Frontali L. Garcia-Gonzalez M. Garcia-Saez M.I. Goffeau A. Guerreiro P. Hani J. Hansen M. Hebling U. Hernandez K. Heumann K. Hilger F. Hofmann B. Indge K.J. James C.M. Klima R. Koetter P. Kramer B. Kramer W. Lauquin G. Leuther H. Louis E.J. Maillier E. Marconi A. Martegani E. Mazon M.J. Mazzoni C. McReynolds A.D.K. Melchioretto P. Mewes H.-W. Minenkova O. Mueller-Auer S. Nawrocki A. Netter P. Neu R. Nombela C. Oliver S.G. Panzeri L. Paoluzi S. Plevani P. Portetelle D. Portillo F. Potier S. Purnelle B. Rieger M. Riles L. Rinaldi T. Robben J. Rodrigues-Pousada C. Rodriguez-Belmonte E. Rodriguez-Torres A.M. Rose M. Ruzzi M. Saliola M. Sanchez-Perez M. Schaefer B. Schaefer M. Scharfe M. Schmidheini T. Schreer A. Skala J. Souciet J.-L. Steensma H.Y. Talla E. Thierry A. Vandenbol M. van der Aart Q.J.M. Van Dyck L. Vanoni M. Verhasselt P. Voet M. Volckaert G. Wambutt R. Watson M.D. Weber N. Wedler E. Wedler H. Wipfli P. Wolf K. Wright L.F. Zaccaria P. Zimmermann M. Zollner A. Kleine K. 1997 Nature 387 81-84 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Whyte J.R. Munro S. doi:10.1016/S1534-5807(01)00063-6 2001 Dev. Cell 1 527-537 SUBUNIT Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Loh E. Hong W. doi:10.1074/jbc.M400662200 2004 J. Biol. Chem. 279 24640-24648 COMPOSITION OF THE COG COMPLEX INTERACTION WITH COG4 COG7 COD5 YGL005C Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. Component of the conserved oligomeric Golgi (COG or Sec34/Sec35) complex which consists of eight different proteins COG1-COG8. Golgi apparatus membrane; Peripheral membrane protein (By similarity). Present with 1360 molecules/cell in log phase SD medium. Conserved oligomeric Golgi complex subunit 7 1 279 false 1 HSP82 EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YGL005C KEGG CYGD SGD COG7 LinkHub GermOnline Saccharomyces cerevisiae SGD SGD SGD 1996-10-01 1 31775 MVELTITGDD DDILSMFFDE EFVPHAFVDI LLSNALNEDQ IQTQSVSSLL LTRLDFYTKN LTKELESTIW NLDKLSQTLP RTWASSRYHK EAEQNDSSLY STESLKSSKL EYYLDTLASA VRALETGMHN VTEKLSDLDN ENNRNTNVRQ QLQSLMLIKE RIEKVVYYLE QVRTVTNIST VRENNTTSTG TDLSITDFRT SLKALEDTID ESLSSAIDNE AKDETNKDLI GRIDSLSELK CLFKGLDKFF AEYSNFSESI KSKAQSYLST KNIDDGMIS true 1996-10-01 2007-10-02 59 YGA4_YEAST WD repeat-containing protein YGL004C Tettelin H. Agostoni-Carbone M.L. Albermann K. Albers M. Arroyo J. Backes U. Barreiros T. Bertani I. Bjourson A.J. Brueckner M. Bruschi C.V. Carignani G. Castagnoli L. Cerdan E. Clemente M.L. Coblenz A. Coglievina M. Coissac E. Defoor E. Del Bino S. Delius H. Delneri D. de Wergifosse P. Dujon B. Durand P. Entian K.-D. Eraso P. Escribano V. Fabiani L. Fartmann B. Feroli F. Feuermann M. Frontali L. Garcia-Gonzalez M. Garcia-Saez M.I. Goffeau A. Guerreiro P. Hani J. Hansen M. Hebling U. Hernandez K. Heumann K. Hilger F. Hofmann B. Indge K.J. James C.M. Klima R. Koetter P. Kramer B. Kramer W. Lauquin G. Leuther H. Louis E.J. Maillier E. Marconi A. Martegani E. Mazon M.J. Mazzoni C. McReynolds A.D.K. Melchioretto P. Mewes H.-W. Minenkova O. Mueller-Auer S. Nawrocki A. Netter P. Neu R. Nombela C. Oliver S.G. Panzeri L. Paoluzi S. Plevani P. Portetelle D. Portillo F. Potier S. Purnelle B. Rieger M. Riles L. Rinaldi T. Robben J. Rodrigues-Pousada C. Rodriguez-Belmonte E. Rodriguez-Torres A.M. Rose M. Ruzzi M. Saliola M. Sanchez-Perez M. Schaefer B. Schaefer M. Scharfe M. Schmidheini T. Schreer A. Skala J. Souciet J.-L. Steensma H.Y. Talla E. Thierry A. Vandenbol M. van der Aart Q.J.M. Van Dyck L. Vanoni M. Verhasselt P. Voet M. Volckaert G. Wambutt R. Watson M.D. Weber N. Wedler E. Wedler H. Wipfli P. Wolf K. Wright L.F. Zaccaria P. Zimmermann M. Zollner A. Kleine K. 1997 Nature 387 81-84 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] YGL004C Present with 2210 molecules/cell in log phase SD medium. Contains 6 WD repeats. WD repeat-containing protein YGL004C 1 417 WD 1 134 173 WD 2 176 215 WD 3 242 281 WD 4 285 325 WD 5 330 371 WD 6 380 416 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YGL004C KEGG CYGD SGD RPN14 LinkHub GermOnline Saccharomyces cerevisiae InterPro WD40 Pfam WD40 2 PRINTS GPROTEINBRPT ProDom WD40 1 SMART WD40 4 PROSITE WD_REPEATS_1 1 PROSITE WD_REPEATS_2 2 PROSITE WD_REPEATS_REGION 1 SGD 1996-10-01 1 46383 MTKTITVAHI QYDFKAVLEE NDENDDEFYI NVDKNLNEIK EHKIVVLGNS RGVDAGKGNT FEKVGSHLYK ARLDGHDFLF NTIIRDGSKM LKRADYTAVD TAKLQMRRFI LGTTEGDIKV LDSNFNLQRE IDQAHVSEIT KLKFFPSGEA LISSSQDMQL KIWSVKDGSN PRTLIGHRAT VTDIAIIDRG RNVLSASLDG TIRLWECGTG TTIHTFNRKE NPHDGVNSIA LFVGTDRQLH EISTSKKNNL EFGTYGKYVI AGHVSGVITV HNVFSKEQTI QLPSKFTCSC NSLTVDGNNA NYIYAGYENG MLAQWDLRSP ECPVGEFLIN EGTPINNVYF AAGALFVSSG FDTSIKLDII SDPESERPAI EFETPTFLVS NDDEVSQFCY VSDDESNGEV LEVGKNNFCA LYNLSNP true 1996-10-01 2007-11-13 52 TIM21_YEAST YG1M_YEAST Import inner membrane translocase subunit TIM21, mitochondrial precursor Deutschbauer A.M. Davis R.W. 2005-07 EMBL/GenBank/DDBJ NUCLEOTIDE SEQUENCE [GENOMIC DNA] SK1 Rieger M. Brueckner M. Schaefer M. Mueller-Auer S. doi:10.1002/(SICI)1097-0061(19970915)13:11<1077::AID-YEA152>3.3.CO;2-P 1997 Yeast 13 1077-1090 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Tettelin H. Agostoni-Carbone M.L. Albermann K. Albers M. Arroyo J. Backes U. Barreiros T. Bertani I. Bjourson A.J. Brueckner M. Bruschi C.V. Carignani G. Castagnoli L. Cerdan E. Clemente M.L. Coblenz A. Coglievina M. Coissac E. Defoor E. Del Bino S. Delius H. Delneri D. de Wergifosse P. Dujon B. Durand P. Entian K.-D. Eraso P. Escribano V. Fabiani L. Fartmann B. Feroli F. Feuermann M. Frontali L. Garcia-Gonzalez M. Garcia-Saez M.I. Goffeau A. Guerreiro P. Hani J. Hansen M. Hebling U. Hernandez K. Heumann K. Hilger F. Hofmann B. Indge K.J. James C.M. Klima R. Koetter P. Kramer B. Kramer W. Lauquin G. Leuther H. Louis E.J. Maillier E. Marconi A. Martegani E. Mazon M.J. Mazzoni C. McReynolds A.D.K. Melchioretto P. Mewes H.-W. Minenkova O. Mueller-Auer S. Nawrocki A. Netter P. Neu R. Nombela C. Oliver S.G. Panzeri L. Paoluzi S. Plevani P. Portetelle D. Portillo F. Potier S. Purnelle B. Rieger M. Riles L. Rinaldi T. Robben J. Rodrigues-Pousada C. Rodriguez-Belmonte E. Rodriguez-Torres A.M. Rose M. Ruzzi M. Saliola M. Sanchez-Perez M. Schaefer B. Schaefer M. Scharfe M. Schmidheini T. Schreer A. Skala J. Souciet J.-L. Steensma H.Y. Talla E. Thierry A. Vandenbol M. van der Aart Q.J.M. Van Dyck L. Vanoni M. Verhasselt P. Voet M. Volckaert G. Wambutt R. Watson M.D. Weber N. Wedler E. Wedler H. Wipfli P. Wolf K. Wright L.F. Zaccaria P. Zimmermann M. Zollner A. Kleine K. 1997 Nature 387 81-84 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Chacinska A. Lind M. Frazier A.E. Dudek J. Meisinger C. Geissler A. Sickmann A. Meyer H.E. Truscott K.N. Guiard B. Pfanner N. Rehling P. doi:10.1016/j.cell.2005.01.011 2005 Cell 120 817-829 IDENTIFICATION BY MASS SPECTROMETRY IDENTIFICATION IN THE TIM23 COMPLEX FUNCTION SUBCELLULAR LOCATION TOPOLOGY INTERACTION WITH TIM23 AND TOM22 Mokranjac D. Popov-Celeketic D. Hell K. Neupert W. doi:10.1074/jbc.C500135200 2005 J. Biol. Chem. 280 23437-23440 IDENTIFICATION BY MASS SPECTROMETRY IDENTIFICATION IN THE TIM23 COMPLEX FUNCTION TIM21 YGR033C Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix. In the complex, it acts as an antagonist of TIM50 by reducing preprotein accumulation at the TOM23 complex and promotes dissociation of the PAM complex from the TIM23 complex. Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21. Interacts directly with TIM23. Interacts with TOM22 component of the TOM complex. Released from the TOM23 complex by the PAM complex, leading to protein translocation into the mitochondrial matrix. Mitochondrion inner membrane; Single-pass membrane protein. Present with 3770 molecules/cell in log phase SD medium. Belongs to the TIM21 family. Mitochondrion 1 70 Import inner membrane translocase subunit TIM21 71 239 Mitochondrial matrix 71 75 76 96 Mitochondrial intermembrane 97 239 A 39 39 false 2 TIM23 false 1 TOM22 EMBL EMBL PIR RefSeq PDB 1.60 A=103-225 SMR 103-225 DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YGR033C KEGG CYGD SGD TIM21 LinkHub GermOnline Saccharomyces cerevisiae InterPro TIM21 Pfam TIM21 1 SGD IntAct SGD 1996-10-01 1 27206 MSSSLPRSLL RLGHRKPLFP RYNTFVNSSV ITHTSLLRTR LYSNGTGATS GKKDDKTRNK PKPLWPQVKS ASTFTFSGIL VIGAVGISAI VIYLILSELF SPSGDTQLFN RAVSMVEKNK DIRSLLQCDD GITGKERLKA YGELITNDKW TRNRPIVSTK KLDKEGRTHH YMRFHVESKK KIALVHLEAK ESKQNYQPDF INMYVDVPGE KRYYLIKPKL HPVSNSKGFL GIRWGPRKD true 1996-02-01 2007-11-13 48 RL38_YEAST 60S ribosomal protein L38 Johnston M. Hillier L.W. Riles L. Albermann K. Andre B. Ansorge W. Benes V. Brueckner M. Delius H. Dubois E. Duesterhoeft A. Entian K.-D. Floeth M. Goffeau A. Hebling U. Heumann K. Heuss-Neitzel D. Hilbert H. Hilger F. Kleine K. Koetter P. Louis E.J. Messenguy F. Mewes H.-W. Miosga T. Moestl D. Mueller-Auer S. Nentwich U. Obermaier B. Piravandi E. Pohl T.M. Portetelle D. Purnelle B. Rechmann S. Rieger M. Rinke M. Rose M. Scharfe M. Scherens B. Scholler P. Schwager C. Schwarz S. Underwood A.P. Urrestarazu L.A. Vandenbol M. Verhasselt P. Vierendeels F. Voet M. Volckaert G. Voss H. Wambutt R. Wedler E. Wedler H. Zimmermann F.K. Zollner A. Hani J. Hoheisel J.D. 1997 Nature 387 87-90 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Planta R.J. Mager W.H. doi:10.1002/(SICI)1097-0061(19980330)14:5<471::AID-YEA241>3.0.CO;2-U 1998 Yeast 14 471-477 NOMENCLATURE SUBUNIT Arnold R.J. Polevoda B. Reilly J.P. Sherman F. doi:10.1074/jbc.274.52.37035 1999 J. Biol. Chem. 274 37035-37040 CLEAVAGE OF INITIATOR METHIONINE Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Gruhler A. Olsen J.V. Mohammed S. Mortensen P. Faergeman N.J. Mann M. Jensen O.N. doi:10.1074/mcp.M400219-MCP200 2005 Mol. Cell. Proteomics 4 310-327 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-49 MASS SPECTROMETRY RPL38 YLR325C L8543.2 Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Cytoplasm. Present with 50200 molecules/cell in log phase SD medium. Belongs to the ribosomal protein L38e family. Removed 1 1 60S ribosomal protein L38 2 78 Phosphoserine 49 49 EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YLR325C KEGG CYGD SGD RPL38 LinkHub GermOnline Saccharomyces cerevisiae InterPro Ribosomal_L38e PANTHER Ribosomal_L38e 1 Pfam Ribosomal_L38e 1 ProDom Ribosomal_L38e 1 SGD SGD SGD 1996-02-01 1 8827 MAREITDIKQ FLELTRRADV KTATVKINKK LNKAGKPFRQ TKFKVRGSSS LYTLVINDAG KAKKLIQSLP PTLKVNRL true 1996-02-01 2007-11-13 47 CSN12_YEAST YJ54_YEAST Cop9 signalosome complex subunit 12 Huang M.-E. Manus V. Chuat J.-C. Galibert F. doi:10.1002/(SICI)1097-0061(199607)12:9<869::AID-YEA964>3.3.CO;2-T 1996 Yeast 12 869-875 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Galibert F. Alexandraki D. Baur A. Boles E. Chalwatzis N. Chuat J.-C. Coster F. Cziepluch C. de Haan M. Domdey H. Durand P. Entian K.-D. Gatius M. Goffeau A. Grivell L.A. Hennemann A. Herbert C.J. Heumann K. Hilger F. Hollenberg C.P. Huang M.-E. Jacq C. Jauniaux J.-C. Katsoulou C. Kirchrath L. Kleine K. Kordes E. Koetter P. Liebl S. Louis E.J. Manus V. Mewes H.-W. Miosga T. Obermaier B. Perea J. Pohl T.M. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rasmussen S.W. Rose M. Rossau R. Schaaff-Gerstenschlaeger I. Smits P.H.M. Scarcez T. Soriano N. To Van D. Tzermia M. Van Broekhoven A. Vandenbol M. Wedler H. von Wettstein D. Wambutt R. Zagulski M. Zollner A. Karpfinger-Hartl L. 1996 EMBO J. 15 2031-2049 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Maytal-Kivity V. Piran R. Pick E. Hofmann K. Glickman M.H. doi:10.1093/embo-reports/kvf235 2002 EMBO Rep. 3 1215-1221 INTERACTION WITH RRI1; CSN9; RRI2 AND CSI1 IDENTIFICATION IN THE COP9 SIGNALOSOME COMPLEX FUNCTION OF THE COP9 SIGNALOSOME COMPLEX Maytal-Kivity V. Pick E. Piran R. Hofmann K. Glickman M.H. doi:10.1016/S1357-2725(02)00378-3 2003 Int. J. Biochem. Cell Biol. 35 706-715 INTERACTION WITH RRI1/CSN5; CSN9; RRI2/CSN10 AND CSI1 IDENTIFICATION IN THE COP9 SIGNALOSOME COMPLEX Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] CSN12 YJR084W J1860 Component of the COP9 signalosome (CSN) complex that is required for cleaving the ubiquitin-like protein RUB1/NEDD8 from neddylated cullin CDC53, a SCF ubiquitin-ligase subunit. The complex is involved in the regulation of the mating pheromone response. Component of the COP9 signalosome (CSN) complex, composed of RRI1/CSN5, CSN9, RRI2/CSN10, PCI8/CSN11, CSN12 and CSI1. In the complex, it probably interacts directly with RRI1/CSN5, CSN9, RRI2/CSN10 and CSI1. Cytoplasm. Nucleus. Present with 1510 molecules/cell in log phase SD medium. Belongs to the CSN12 family. Contains 1 PCI domain. Cop9 signalosome complex subunit 12 1 423 PCI 298 415 false 2 false 2 CSI1 false 2 CSN9 false 3 RRI1 false 2 RRI2 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YJR084W KEGG CYGD SGD CSN12 LinkHub GermOnline Saccharomyces cerevisiae InterPro PAM InterPro PCI Pfam PCI 1 SMART PAM 1 SGD IntAct SGD 1996-02-01 1 49482 MDVDIGCYFE EKRYDDKLLD FIRYDVKTPK KTKYILQRPT ATDEESVRLQ RFYQLGVDLK LKYSKRRSLK KQGRIKNATE ELLRLANEQL KLFNRIVERE TNWIIYPLWV MAKQLIRLAN ESSELNKDSI EECGRTIHRS FTICLNDRNP RLNENKKIGC YMFANLEFSI YHRLSNKDMI KNLVKVLESR VNARDIPPLN KSLAMEHKSQ VVLYNYYLGQ YYGCLENDHE RGFFHLNEAL LQCPMLYVES TGKFVLQGQM EKIMILLVPL ALLTKRLYPH WDHPVIAGVI TRSKRLSQVY PTLVRSVISG NLSLYEATAA SHERFFLSQG LHVVITLLRE VVFTRLVQRC WQWGNDRKSI MPLKILLATK QHDSSANEDE EEQLDALECR LASAIASGLL RAYLSHSNRC IVFSKKEPFP HSK true 1996-02-01 2007-11-13 55 TMA22_YEAST DENR_YEAST YJY4_YEAST Translation machinery-associated protein 22 Density-regulated protein homolog Galibert F. Alexandraki D. Baur A. Boles E. Chalwatzis N. Chuat J.-C. Coster F. Cziepluch C. de Haan M. Domdey H. Durand P. Entian K.-D. Gatius M. Goffeau A. Grivell L.A. Hennemann A. Herbert C.J. Heumann K. Hilger F. Hollenberg C.P. Huang M.-E. Jacq C. Jauniaux J.-C. Katsoulou C. Kirchrath L. Kleine K. Kordes E. Koetter P. Liebl S. Louis E.J. Manus V. Mewes H.-W. Miosga T. Obermaier B. Perea J. Pohl T.M. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rasmussen S.W. Rose M. Rossau R. Schaaff-Gerstenschlaeger I. Smits P.H.M. Scarcez T. Soriano N. To Van D. Tzermia M. Van Broekhoven A. Vandenbol M. Wedler H. von Wettstein D. Wambutt R. Zagulski M. Zollner A. Karpfinger-Hartl L. 1996 EMBO J. 15 2031-2049 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] TMA22 YJR014W J1446 YJR83.12 Present with 21600 molecules/cell in log phase SD medium. Contains 1 SUI1 domain. Translation machinery-associated protein 22 1 198 SUI1 99 170 EMBL EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YJR014W KEGG CYGD SGD TMA22 LinkHub GermOnline Saccharomyces cerevisiae InterPro Drp1 InterPro TIF_SUI1 Pfam SUI1 1 TIGRFAMs DRP1 1 PROSITE SUI1 1 SGD 1996-02-01 1 22495 MLREVIYCGI CSYPPEYCEF SGKLKRCKVW LSENHADLYA KLYGTDDNTQ EVEAVTNKLA ESSIGEAREE KLEKDLLKIQ KKQENREQRE LAKKLSSKVI IKREARTKRK FIVAISGLEV FDIDMKKLAK TFASRFATGC SVSKNAEKKE EVVIQGDVMD EVETYIHSLL EEKGLKDVKV ETIDAKKKKK PAAEGAAK true 1995-11-01 2007-11-13 53 IES1_YEAST YFB3_YEAST Ino eighty subunit 1 Murakami Y. Naitou M. Hagiwara H. Shibata T. Ozawa M. Sasanuma S. Sasanuma M. Tsuchiya Y. Soeda E. Yokoyama K. Yamazaki M. Tashiro H. Eki T. doi:10.1038/ng0795-261 1995 Nat. Genet. 10 261-268 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Shen X. Ranallo R. Choi E. Wu C. doi:10.1016/S1097-2765(03)00264-8 2003 Mol. Cell 12 147-155 PARTIAL PROTEIN SEQUENCE IDENTIFICATION IN THE INO80 COMPLEX Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Smolka M.B. Albuquerque C.P. Chen S.H. Zhou H. doi:10.1073/pnas.0701622104 2007 Proc. Natl. Acad. Sci. U.S.A. 104 10364-10369 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-27; SER-493; SER-504 AND THR-507 MASS SPECTROMETRY IES1 YFL013C Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex. Component of the chromatin-remodeling INO80 complex, at least composed of ARP4, ARP5, ARP8, RVB1, RVB2, TAF14, NHP10, IES1, IES3, IES4, IES6, ACT1, IES2, IES5 and INO80. Nucleus. Present with 1400 molecules/cell in log phase SD medium. Ino eighty subunit 1 1 692 340 385 Phosphoserine 27 27 Phosphoserine 493 493 Phosphoserine 504 504 Phosphothreonine 507 507 EMBL EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YFL013C KEGG CYGD SGD IES1 LinkHub GermOnline Saccharomyces cerevisiae SGD SGD 1995-11-01 1 78753 MGKRVYDPIH DTFQLREDNS DETKADSPMQ SVKSGSQEEA SPSSIQSETE TVTTKSIPVI HEIEIDDKND DDSTQSEEEN TNILLNFEPS TVPEATGAST ATGPVTTNTV RRKPKESNAS KYNRHLKKPD GEPFNRKDIQ FSFMQELLMD KRQIFTNVLK PLYKNSIVPI NIDGDKLSIN VTDKEYDART FVFNDKLTFA QLYVLTIATS IKCSKILRDK LLLDQQVAFS TCVLALLVNI GRLNTTINFY LEMTSQLRTF HSVPVLQLHA NDPKLLQDTP RLKSILKNLP WGNEQLSLME TYKKVDQNDG EVDTVNKFNI INMLFSICDN SGLIDKRFLS KYVEVESKAQ EQDMVDEQNE VKETEAENEK QESKAAYATT LFDILDYSKY EPKDRSNILI WLLYIHLETN LSQEEVEESV RFFNGLEDGA PAGKFILRCT ERSYDTDPED ELEFGANQRI KRREFMSKME EGRKRERTNV TEVKKPSIGG DKSEEDGEGE DDKSEETVEE TRSLLTPTPI LESSSPMTLN RKKVTPQLPK VTPAAPTETE EEITSAAIID KNDLNLTPLK KYNSSATVNK VDKLISLDLN KHVSENGKTQ EEFLADLKKS QVPNRLKRRD IGLIKIFNEF EDIPVASVLG IRGKKRKKFK DNLLGFETDF MKNLGASKKV LLNKIERAEI DDEEATAMFK LE true 1995-11-01 2007-10-02 56 MDJ2_YEAST YNOA_YEAST YN68_YEAST Mitochondrial DnaJ homolog 2 Maftahi M. Nicaud J.-M. Levesque H. Gaillardin C. 1995 Yeast 11 567-572 NUCLEOTIDE SEQUENCE [GENOMIC DNA] S288c / FY1676 Philippsen P. Kleine K. Poehlmann R. Duesterhoeft A. Hamberg K. Hegemann J.H. Obermaier B. Urrestarazu L.A. Aert R. Albermann K. Altmann R. Andre B. Baladron V. Ballesta J.P.G. Becam A.-M. Beinhauer J.D. Boskovic J. Buitrago M.J. Bussereau F. Coster F. Crouzet M. D'Angelo M. Dal Pero F. De Antoni A. del Rey F. Doignon F. Domdey H. Dubois E. Fiedler T.A. Fleig U. Floeth M. Fritz C. Gaillardin C. Garcia-Cantalejo J.M. Glansdorff N. Goffeau A. Gueldener U. Herbert C.J. Heumann K. Heuss-Neitzel D. Hilbert H. Hinni K. Iraqui Houssaini I. Jacquet M. Jimenez A. Jonniaux J.-L. Karpfinger-Hartl L. Lanfranchi G. Lepingle A. Levesque H. Lyck R. Maftahi M. Mallet L. Maurer C.T.C. Messenguy F. Mewes H.-W. Moestl D. Nasr F. Nicaud J.-M. Niedenthal R.K. Pandolfo D. Pierard A. Piravandi E. Planta R.J. Pohl T.M. Purnelle B. Rebischung C. Remacha M.A. Revuelta J.L. Rinke M. Saiz J.E. Sartorello F. Scherens B. Sen-Gupta M. Soler-Mira A. Urbanus J.H.M. Valle G. Van Dyck L. Verhasselt P. Vierendeels F. Vissers S. Voet M. Volckaert G. Wach A. Wambutt R. Wedler H. Zollner A. Hani J. 1997 Nature 387 93-98 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Westermann B. Neupert W. doi:10.1006/jmbi.1997.1267 1997 J. Mol. Biol. 272 477-483 FUNCTION SUBCELLULAR LOCATION Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Mokranjac D. Sichting M. Popov-Celeketic D. Berg A. Hell K. Neupert W. doi:10.1074/jbc.M502397200 2005 J. Biol. Chem. 280 31608-31614 FUNCTION IDENTIFICATION IN THE PAM23 COMPLEX INTERACTION WITH PAM16 MDJ2 YNL328C N0315 Plays a role in mitochondrial biogenesis and protein folding. Participates in the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner, probably by stimulating activity of mtHSP70 (SSC1). Interacts with PAM16/TIM16 and is recruited by the PAM complex. Mitochondrion inner membrane. Present with 573 molecules/cell in log phase SD medium. Contains 1 J domain. Mitochondrial DnaJ homolog 2 1 146 J 85 146 EMBL EMBL EMBL PIR RefSeq DIP Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YNL328C KEGG CYGD SGD MDJ2 LinkHub GermOnline Saccharomyces cerevisiae InterPro DnaJ_N Pfam DnaJ 1 SMART DnaJ 1 PROSITE DNAJ_1 true PROSITE DNAJ_2 1 SGD SGD SGD 1995-11-01 1 16474 MVLPIIIGLG VTMVALSVKS GLNAWTVYKT LSPLTIAKLN NIRIENPTAG YRDALKFKSS LIDEELKNRL NQYQGGFAPR MTEPEALLIL DISAREINHL DEKLLKKKHR KAMVRNHPDR GGSPYMAAKI NEAKEVLERS VLLRKR true 1995-11-01 2007-11-13 42 YN51_YEAST YNOJ_YEAST F-box protein YNL311C Maftahi M. Nicaud J.-M. Levesque H. Gaillardin C. 1995 Yeast 11 1077-1085 NUCLEOTIDE SEQUENCE [GENOMIC DNA] S288c / FY1676 Philippsen P. Kleine K. Poehlmann R. Duesterhoeft A. Hamberg K. Hegemann J.H. Obermaier B. Urrestarazu L.A. Aert R. Albermann K. Altmann R. Andre B. Baladron V. Ballesta J.P.G. Becam A.-M. Beinhauer J.D. Boskovic J. Buitrago M.J. Bussereau F. Coster F. Crouzet M. D'Angelo M. Dal Pero F. De Antoni A. del Rey F. Doignon F. Domdey H. Dubois E. Fiedler T.A. Fleig U. Floeth M. Fritz C. Gaillardin C. Garcia-Cantalejo J.M. Glansdorff N. Goffeau A. Gueldener U. Herbert C.J. Heumann K. Heuss-Neitzel D. Hilbert H. Hinni K. Iraqui Houssaini I. Jacquet M. Jimenez A. Jonniaux J.-L. Karpfinger-Hartl L. Lanfranchi G. Lepingle A. Levesque H. Lyck R. Maftahi M. Mallet L. Maurer C.T.C. Messenguy F. Mewes H.-W. Moestl D. Nasr F. Nicaud J.-M. Niedenthal R.K. Pandolfo D. Pierard A. Piravandi E. Planta R.J. Pohl T.M. Purnelle B. Rebischung C. Remacha M.A. Revuelta J.L. Rinke M. Saiz J.E. Sartorello F. Scherens B. Sen-Gupta M. Soler-Mira A. Urbanus J.H.M. Valle G. Van Dyck L. Verhasselt P. Vierendeels F. Vissers S. Voet M. Volckaert G. Wach A. Wambutt R. Wedler H. Zollner A. Hani J. 1997 Nature 387 93-98 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] YNL311C N0376 Present with 432 molecules/cell in log phase SD medium. Contains 1 F-box domain. F-box protein YNL311C 1 763 F-box 54 100 Poly-Glu 22 28 false 1 false 1 false 1 MET14 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YNL311C KEGG CYGD SGD YNL311C LinkHub GermOnline Saccharomyces cerevisiae InterPro F-box Pfam F-box 1 SMART FBOX 1 PROSITE FBOX 1 IntAct 1995-11-01 1 88942 MKRLQLFGRS KYFSLVSSAA KEEEEEEEGC ADAKSLLHST SHDIKSRSLR FNDKSSLMCL PTKVLLLILR TLDFNTLVTL CQVNSRFYNL ITNEFLFQNV ILDSKLSLLK FNALIHSEFH TSNIVTHSGD CSTQSRSQNA RFLVRSIEFK NPQSQDSLLK YSKFYNKSGQ DSIIAGSYKL DSYDKDVKKL NNIRLNDETP IITSERIKLL DKLESNYFHY TYIELMLDII DYLPNLTRVI LSDVEPNFKI PLWYSVFNDG SRDFFKKIIK GQQSITNEDL RTFQLSKKFV KEYESKYYSL PRLKILEIKA NNKRQRTFNR QRHHQKLVLR PSLFCCFGII NELKLENVTI DTESLDTPME FLPLFLKNED NELYSLQSPI TALTLDSCDV VPGNGILRLF HSYFKMVKHL SLLKINSKFD LLLCSCFPSL SNLTIDCNSK CFTNEQVVGE SYYFQQRSLD TEDDFDDCNS MTETLFEAPS DSKIITPPPT SSVVLSLNLN YISRTTGNDV SNNPSPDNNK KPAMLTAAQL QNFQRQRIPE FHSFYHYYRL LWERLPSKNI SINVINIPFT NVYPLSPLSF WEHLARTITS VDETDEDVGD ENDQETLIGY ENNSIRDNIP NANAVPNLST VMSPESDIHH TYYWNNSVRR CLRDSLIKLK NRTIEYRDLD VEEFLQNVTL ENFFNDFQDP ENFKDIPNIN LWCFLRNLSK FKAVKIRMLR HFSLCTPRTR YDWELLLKPV LRVNVPIEVR DKDGFVLYSY GQK true 1995-02-01 2007-10-02 57 YIN7_YEAST Putative zinc aminopeptidase YIL137C EC 3.4.11.- Churcher C.M. Bowman S. Badcock K. Bankier A.T. Brown D. Chillingworth T. Connor R. Devlin K. Gentles S. Hamlin N. Harris D.E. Horsnell T. Hunt S. Jagels K. Jones M. Lye G. Moule S. Odell C. Pearson D. Rajandream M.A. Rice P. Rowley N. Skelton J. Smith V. Walsh S.V. Whitehead S. Barrell B.G. 1997 Nature 387 84-87 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] YIL137C Binds 1 zinc ion per subunit (By similarity). Present with 5110 molecules/cell in log phase SD medium. Belongs to the peptidase M1 family. Putative zinc aminopeptidase YIL137C 1 946 331 331 Zinc (catalytic) 330 330 Zinc (catalytic) 334 334 Zinc (catalytic) 353 353 EMBL PIR RefSeq DIP IntAct MEROPS PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YIL137C KEGG CYGD SGD TMA108 LinkHub GermOnline Saccharomyces cerevisiae InterPro Pept_M_Zn_BS InterPro Peptidase_M1 InterPro Peptidase_M1_N PANTHER Peptidase_M1 1 Pfam Peptidase_M1 1 PRINTS ALADIPTASE PROSITE ZINC_PROTEASE 1 SGD 1995-02-01 1 107723 MSDNLLSLEN PVVPSHYELR LEIDPKQSSP NFKGSAIIHL KFNPNSTTLA SIEDSFTQFK LHSKDLIVLS AHATIGSTKF DLKISQDTGK HLSIFNSESP IQLSNDCPLI LSVQYVGKIR DIKTHHDKTF GIFKTNFMDR KTGTANNHVV ATHCQPFSAS NIFPCIDEPS NKSTFQLNIA TDAQYKAVSN TPVEMVEALD SSQKHLVKFA KTPLMTTSVF GFSIGDLEFL KTEIKLEGDR TIPVSIYAPW DIANAAFTLD TVQKYLPLLE SYFKCPYPLP KLDFVLLPYL SDMAMENFGM ITIQLNHLLI PPNALANETV REQAQQLIVH ELVHQWMGNY ISFDSWESLW FNESFATWLA CHILEQNGDL SHYWTSEPYL LQQVEPTMCR DAADVNGRSI FQIAQRNTGI DSQTSDIFDP EAYTKGIIML RSLQLATGES HLQKGLESVF EDTKTFHARS VKPMDIWNHI GKFLKSQNIT NFVSSWTRTP GLPVVKVEVE EKDGKTQTKL TQHRFINQLS TEEKDQLEDV PYQVPLFGVL PDGKMDTKNV LLTDRTLKFD YPILVINHLA QGYYRVSYES EECYALINDK ITEETLSEID LRKIFLDLSQ FIGDEGFQNS IHLHGLFKIL NHIASPSTKI ASKYWDPLSK GLEVLQTIDR ASLTSSKLQS FLKKKIVIPL FNKIDWPHGE FDKSTNPHEL KVMSQVLFLN KNSAKCAELC QIYFKHLLQG PRSSVPLELV NSILVVVSQH CANIKQWKKI FDLVKRSSCT GITNHVINMY DQNSSETAML IQNGAIESLG FCLDSDIVKK TLNFITSNIE SEGMELALFG FNYNFKKRLN KNEKPQDQVV RETIWEWYMG NFDQWARKAT RKGTTTGDHL HKALRSISLI IFQMFVADEP QKIEKFINLE KEKLGQSLLS LDDIWASVQQ DEESRKTIRR DLASLV true 1995-02-01 2007-11-13 52 PSF2_YEAST YJH2_YEAST YJ02_YEAST DNA replication complex GINS protein PSF2 Partner of Sld five 2 Takayama Y. Kamimura Y. Okawa M. Muramatsu S. Sugino A. Araki H. doi:10.1101/gad.1065903 2003 Genes Dev. 17 1153-1165 NUCLEOTIDE SEQUENCE [GENOMIC DNA] FUNCTION AND COMPOSITION OF THE GINS COMPLEX SUBCELLULAR LOCATION Sor F.J. 1995-06 EMBL/GenBank/DDBJ NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Vandenbol M. Durand P. Dion C. Portetelle D. Hilger F. 1995 Yeast 11 57-60 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Galibert F. Alexandraki D. Baur A. Boles E. Chalwatzis N. Chuat J.-C. Coster F. Cziepluch C. de Haan M. Domdey H. Durand P. Entian K.-D. Gatius M. Goffeau A. Grivell L.A. Hennemann A. Herbert C.J. Heumann K. Hilger F. Hollenberg C.P. Huang M.-E. Jacq C. Jauniaux J.-C. Katsoulou C. Kirchrath L. Kleine K. Kordes E. Koetter P. Liebl S. Louis E.J. Manus V. Mewes H.-W. Miosga T. Obermaier B. Perea J. Pohl T.M. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rasmussen S.W. Rose M. Rossau R. Schaaff-Gerstenschlaeger I. Smits P.H.M. Scarcez T. Soriano N. To Van D. Tzermia M. Van Broekhoven A. Vandenbol M. Wedler H. von Wettstein D. Wambutt R. Zagulski M. Zollner A. Karpfinger-Hartl L. 1996 EMBO J. 15 2031-2049 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c PSF2 YJL072C J1086 HRF213 Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery. Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3. Nucleus. Belongs to the PSF2 family. DNA replication complex GINS protein PSF2 1 213 false 1 SLD5 EMBL EMBL EMBL EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YJL072C KEGG CYGD SGD PSF2 LinkHub GermOnline Saccharomyces cerevisiae InterPro GINS_Psf2 PANTHER GINS_Psf2 1 Pfam Psf2 1 SGD SGD IntAct SGD 1995-02-01 1 25061 MSLPAHLQQT FSPEEIQFIV ENEPIKIFPR ITTRQKIRGD DRGTGNHTRW QLITTDDKAL NNMVAMRSTE VVLWIALLLK QQSKCSIVAP QWLTTKELDR KIQYEKTHPD RFSELPWNWL VLARILFNKA KDDFHDPIHE LRGKIQDLRE IRQIKVLKGL KYLNESHLQL DNLSLLEINE LRPFITEIMD KLREIHTASL TAGTENDEEE FNI true 1995-02-01 2007-11-13 62 YHH5_YEAST Uncharacterized RNA-binding protein YHR015W Johnston M. Andrews S. Brinkman R. Cooper J. Ding H. Dover J. Du Z. Favello A. Fulton L. Gattung S. Geisel C. Kirsten J. Kucaba T. Hillier L.W. Jier M. Johnston L. Langston Y. Latreille P. Louis E.J. Macri C. Mardis E. Menezes S. Mouser L. Nhan M. Rifkin L. Riles L. St Peter H. Trevaskis E. Vaughan K. Vignati D. Wilcox L. Wohldman P. Waterston R. Wilson R. Vaudin M. 1994 Science 265 2077-2082 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] YHR015W Present with 98 molecules/cell in log phase SD medium. Contains 3 RRM (RNA recognition motif) domains. Uncharacterized RNA-binding protein YHR015W 1 659 RRM 1 111 189 RRM 2 199 267 RRM 3 313 389 EMBL PIR RefSeq HSSP 1CVJ DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YHR015W KEGG CYGD SGD MIP6 LinkHub GermOnline Saccharomyces cerevisiae InterPro a_b_plait_nuc_bd InterPro RRM_RNP1 Gene3D a_b_plait_nuc_bd 3 Pfam RRM_1 3 SMART RRM 3 PROSITE RRM 3 SGD SGD 1995-02-01 1 75920 MPNSHGNVLN NISLNSKQNP RSISKSCPND KDARQKSFKT ISAQALVRVQ GAGYKLGDVK LKDAEVKEKN SLKKYDCKNA TQEKKEQEQV FEKTVAKGSV QKYITKTSKT NSLFIGNLKS TVTEEMLRKI FKRYQSFESA KVCRDFLTKK SLGYGYLNFK DKNDAESARK EFNYTVFFGQ EVKIMPSMKN TLFRKNIGTN VFFSNLPLEN PQLTTRSFYL IMIEYGNVLS CLLERRKNIG FVYFDNDISA RNVIKKYNNQ EFFGNKIICG LHFDKEVRTR PEFTKRKKMI GSDIVIEDEL LASNNLSDNA RSKTILVKNL PSDTTQEEVL DYFSTIGPIK SVFISEKQAN TPHKAFVTYK NEEESKKAQK CLNKTIFKNH TIWVGPGKDK PVHNQIGTNK KTKVYLKNLS FNCNKEFISQ LCLQEKIRFS EIKITNYNSL NWTFCGHVEC FSRSDAERLF NILDRRLIGS SLVEASWSKN NDNILNEIDY DDGNNNENYK KLINISSMMR FRTQELSAHQ KGLTSQFQQV VSPFSSYSNS YTNMNSLVAT PMKPHPAFNL ITNTVDEKLH QPKRTKQENA EILESLKKII NRNLQRISIS GLNKEENLRS ISEFIFDVFW EHDSERLSHF LLMTNTSLES QKILQKQVTR AAESLGFTV true 1995-02-01 2007-11-13 51 CIC1_YEAST YHL2_YEAST Proteasome-interacting protein CIC1 Core interacting component 1 Johnston M. Andrews S. Brinkman R. Cooper J. Ding H. Dover J. Du Z. Favello A. Fulton L. Gattung S. Geisel C. Kirsten J. Kucaba T. Hillier L.W. Jier M. Johnston L. Langston Y. Latreille P. Louis E.J. Macri C. Mardis E. Menezes S. Mouser L. Nhan M. Rifkin L. Riles L. St Peter H. Trevaskis E. Vaughan K. Vignati D. Wilcox L. Wohldman P. Waterston R. Wilson R. Vaudin M. 1994 Science 265 2077-2082 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Jaeger S. Strayle J. Heinemeyer W. Wolf D.H. doi:10.1093/emboj/20.16.4423 2001 EMBO J. 20 4423-4431 FUNCTION INTERACTION WITH PROTEASOME SUBUNITS SUBCELLULAR LOCATION Harnpicharnchai P. Jakovljevic J. Horsey E. Miles T. Roman J. Rout M. Meagher D. Imai B. Guo Y. Brame C.J. Shabanowitz J. Hunt D.F. Woolford J.L. Jr. doi:10.1016/S1097-2765(01)00344-6 2001 Mol. Cell 8 505-515 INTERACTION WITH NOP7 Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Fatica A. Oeffinger M. Tollervey D. Bozzoni I. doi:10.1261/rna.5130503 2003 RNA 9 1431-1436 FUNCTION Smolka M.B. Albuquerque C.P. Chen S.H. Zhou H. doi:10.1073/pnas.0701622104 2007 Proc. Natl. Acad. Sci. U.S.A. 104 10364-10369 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-5; SER-7; SER-10; THR-11; SER-14; THR-15; SER-357; SER-359 AND SER-366 MASS SPECTROMETRY CIC1 NSA3 YHR052W An adapter protein that specifically links the 26S proteasome to its substrate CDC4 which is one of the substrate recognition subunits of the SCF E3 ubiquitin ligase complex. Required for turnover of cell cycle regulatory proteins CDC4 and GRR1. Required for synthesis and nuclear export of 60S ribosomal subunits. Required for vegetative growth. Interacts with CDC4, PRE4, PRE6, RPT1 and SCL1 as part of the fully assembled 26S proteasome. Interacts with pre-ribosomal particles constituent NOP7. Nucleus, nucleolus. Present with 45900 molecules/cell in log phase SD medium. Proteasome-interacting protein CIC1 1 376 Required for interaction with CDC4 310 376 Phosphoserine 5 5 Phosphoserine 7 7 Phosphoserine 10 10 Phosphothreonine 11 11 Phosphoserine 14 14 Phosphothreonine 15 15 Phosphoserine 357 357 Phosphoserine 359 359 Phosphoserine 366 366 false 1 CDC4 false 1 PRE6 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YHR052W KEGG CYGD SGD CIC1 LinkHub GermOnline Saccharomyces cerevisiae SGD SGD SGD SGD SGD 1995-02-01 1 42530 MAKKSNSKKS TPVSTPSKEK KKVIEKKSST AIPRERVIKA VNELIKFTSK PQDENNEEGN NGKKNLLEDD EEELKKDLQL IVVNNKSFTG TSKSFKLKLL NVKHSFYKPW KEASATAVKD FKVLLILKDS DIKKVSEDDL FDQLDSEGIK VDEIICGKDL KTVYKAYEAR NAFISQFSLI LADDSIVTSL PKLMGGKAYN KVETTPISIR THANKEFSLT TLTNNIKKVY MNQLPVKLPR GTTLNVHLGN LEWLRPEEFV DNVELISEQL IKAYQIRSIF IKTNRSPVLP LYYNQDVLDE LEAKKDKIEE THEDDMVTID GVQVHLSTFN KGLMEIANPS ELGSIFSKQI NNAKKRSSSE LEKESSESEA VKKAKS true 1994-06-01 2007-10-02 43 PAM17_YEAST YK45_YEAST Presequence translocated-associated motor subunit PAM17, mitochondrial precursor Dujon B. Alexandraki D. Andre B. Ansorge W. Baladron V. Ballesta J.P.G. Banrevi A. Bolle P.-A. Bolotin-Fukuhara M. Bossier P. Bou G. Boyer J. Buitrago M.J. Cheret G. Colleaux L. Daignan-Fornier B. del Rey F. Dion C. Domdey H. Duesterhoeft A. Duesterhus S. Entian K.-D. Erfle H. Esteban P.F. Feldmann H. Fernandes L. Fobo G.M. Fritz C. Fukuhara H. Gabel C. Gaillon L. Garcia-Cantalejo J.M. Garcia-Ramirez J.J. Gent M.E. Ghazvini M. Goffeau A. Gonzalez A. Grothues D. Guerreiro P. Hegemann J.H. Hewitt N. Hilger F. Hollenberg C.P. Horaitis O. Indge K.J. Jacquier A. James C.M. Jauniaux J.-C. Jimenez A. Keuchel H. Kirchrath L. Kleine K. Koetter P. Legrain P. Liebl S. Louis E.J. Maia e Silva A. Marck C. Monnier A.-L. Moestl D. Mueller S. Obermaier B. Oliver S.G. Pallier C. Pascolo S. Pfeiffer F. Philippsen P. Planta R.J. Pohl F.M. Pohl T.M. Poehlmann R. Portetelle D. Purnelle B. Puzos V. Ramezani Rad M. Rasmussen S.W. Remacha M.A. Revuelta J.L. Richard G.-F. Rieger M. Rodrigues-Pousada C. Rose M. Rupp T. Santos M.A. Schwager C. Sensen C. Skala J. Soares H. Sor F. Stegemann J. Tettelin H. Thierry A. Tzermia M. Urrestarazu L.A. van Dyck L. van Vliet-Reedijk J.C. Valens M. Vandenbol M. Vilela C. Vissers S. von Wettstein D. Voss H. Wiemann S. Xu G. Zimmermann J. Haasemann M. Becker I. Mewes H.-W. doi:10.1038/369371a0 1994 Nature 369 371-378 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] van der Laan M. Chacinska A. Lind M. Perschil I. Sickmann A. Meyer H.E. Guiard B. Meisinger C. Pfanner N. Rehling P. doi:10.1128/MCB.25.17.7449-7458.2005 2005 Mol. Cell. Biol. 25 7449-7458 IDENTIFICATION BY MASS SPECTROMETRY IDENTIFICATION IN THE PAM COMPLEX FUNCTION SUBCELLULAR LOCATION PAM17 FMP18 YKR065C Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to organize PAM16-PAM18 (TIM16-TIM14) heterodimer. Component of the PAM complex, at least composed of mtHsp70, MGE1, TIM44, PAM16, PAM17 and PAM18/TIM14. Mitochondrion inner membrane; Multi-pass membrane protein (Potential). Present with 3000 molecules/cell in log phase SD medium. Belongs to the PAM17 family. Mitochondrion 1 14 Presequence translocated-associated motor subunit PAM17 15 197 64 84 103 123 EMBL PIR RefSeq DIP PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YKR065C KEGG CYGD SGD PAM17 LinkHub GermOnline Saccharomyces cerevisiae InterPro Pam17 Pfam Pam17 1 SGD SGD 1994-06-01 1 21968 MFTSAIRLSS QRLFASQPSV TAAALRSTAT TLPLRSYSQP ASLQDSSILT WSDFFKLRKQ QRRINVGSSL FTALLGCNVS WAYLSTMEID PTQMLFGFDP LTVISAGIIA SGALGYLLGP IVGSQVFKLS HNQQLAQFNN KNKEFLKHII NNRVDASSQS FSNPVPDYYG EKIGSLKEYK QWLRDCHAYA KKAKEFL true 1994-06-01 2007-11-13 59 MRP8_YEAST RT08_YEAST Uncharacterized protein MRP8 Abraham P.R. Mulder A. Van'T Riet J. Planta R.J. Raue H.A. 1992 Yeast 8 227-238 NUCLEOTIDE SEQUENCE [GENOMIC DNA] Dujon B. Alexandraki D. Andre B. Ansorge W. Baladron V. Ballesta J.P.G. Banrevi A. Bolle P.-A. Bolotin-Fukuhara M. Bossier P. Bou G. Boyer J. Buitrago M.J. Cheret G. Colleaux L. Daignan-Fornier B. del Rey F. Dion C. Domdey H. Duesterhoeft A. Duesterhus S. Entian K.-D. Erfle H. Esteban P.F. Feldmann H. Fernandes L. Fobo G.M. Fritz C. Fukuhara H. Gabel C. Gaillon L. Garcia-Cantalejo J.M. Garcia-Ramirez J.J. Gent M.E. Ghazvini M. Goffeau A. Gonzalez A. Grothues D. Guerreiro P. Hegemann J.H. Hewitt N. Hilger F. Hollenberg C.P. Horaitis O. Indge K.J. Jacquier A. James C.M. Jauniaux J.-C. Jimenez A. Keuchel H. Kirchrath L. Kleine K. Koetter P. Legrain P. Liebl S. Louis E.J. Maia e Silva A. Marck C. Monnier A.-L. Moestl D. Mueller S. Obermaier B. Oliver S.G. Pallier C. Pascolo S. Pfeiffer F. Philippsen P. Planta R.J. Pohl F.M. Pohl T.M. Poehlmann R. Portetelle D. Purnelle B. Puzos V. Ramezani Rad M. Rasmussen S.W. Remacha M.A. Revuelta J.L. Richard G.-F. Rieger M. Rodrigues-Pousada C. Rose M. Rupp T. Santos M.A. Schwager C. Sensen C. Skala J. Soares H. Sor F. Stegemann J. Tettelin H. Thierry A. Tzermia M. Urrestarazu L.A. van Dyck L. van Vliet-Reedijk J.C. Valens M. Vandenbol M. Vilela C. Vissers S. von Wettstein D. Voss H. Wiemann S. Xu G. Zimmermann J. Haasemann M. Becker I. Mewes H.-W. doi:10.1038/369371a0 1994 Nature 369 371-378 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Zhou W. Ryan J.J. Zhou H. doi:10.1074/jbc.M404173200 2004 J. Biol. Chem. 279 32262-32268 SUMOYLATION [LARGE SCALE ANALYSIS] AT LYS-137 MASS SPECTROMETRY Smolka M.B. Albuquerque C.P. Chen S.H. Zhou H. doi:10.1073/pnas.0701622104 2007 Proc. Natl. Acad. Sci. U.S.A. 104 10364-10369 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-13 MASS SPECTROMETRY MRP8 YKL142W YKL3 Cytoplasm. Present with 1550 molecules/cell in log phase SD medium. Was originally (#{citation 1}) thought to be a mitochondrial ribosomal protein. Uncharacterized protein MRP8 1 219 Phosphoserine 13 13 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) 137 137 false 2 PIL1 EMBL EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YKL142W KEGG CYGD SGD MRP8 LinkHub GermOnline Saccharomyces cerevisiae InterPro Ribosomal_MRP8 Pfam Ribosomal_MRP8 1 IntAct 1994-06-01 1 25097 MSNEIELLQK QVSELQDLVK KQSLIISKTG ERVLELQLDK QKHDVTDFDS KFSKSISKKS GSATQFDATD FATNEDLVEL VKELQGELNF IEERSIRRLV NSLKKDDDDV IAPLPNADGD IPAISDGVFP KSLKEFKDIP DLKLVRLAKF YERLPPTLKE QEDFENFLEG KVEAFHINET TDEEISKELE KFSKDELDDA FNDVARYLGL SLRRGTEIW true 1994-02-01 2007-11-13 57 YKB7_YEAST YKAF_YEAST Uncharacterized ATP-dependent helicase YKL017C EC 3.6.1.- Wiemann S. Voss H. Schwager C. Rupp T. Stegemann J. Zimmermann J. Grothues D. Sensen C. Erfle H. Hewitt N. Banrevi A. Ansorge W. 1993 Yeast 9 1343-1348 NUCLEOTIDE SEQUENCE [GENOMIC DNA] Dujon B. Alexandraki D. Andre B. Ansorge W. Baladron V. Ballesta J.P.G. Banrevi A. Bolle P.-A. Bolotin-Fukuhara M. Bossier P. Bou G. Boyer J. Buitrago M.J. Cheret G. Colleaux L. Daignan-Fornier B. del Rey F. Dion C. Domdey H. Duesterhoeft A. Duesterhus S. Entian K.-D. Erfle H. Esteban P.F. Feldmann H. Fernandes L. Fobo G.M. Fritz C. Fukuhara H. Gabel C. Gaillon L. Garcia-Cantalejo J.M. Garcia-Ramirez J.J. Gent M.E. Ghazvini M. Goffeau A. Gonzalez A. Grothues D. Guerreiro P. Hegemann J.H. Hewitt N. Hilger F. Hollenberg C.P. Horaitis O. Indge K.J. Jacquier A. James C.M. Jauniaux J.-C. Jimenez A. Keuchel H. Kirchrath L. Kleine K. Koetter P. Legrain P. Liebl S. Louis E.J. Maia e Silva A. Marck C. Monnier A.-L. Moestl D. Mueller S. Obermaier B. Oliver S.G. Pallier C. Pascolo S. Pfeiffer F. Philippsen P. Planta R.J. Pohl F.M. Pohl T.M. Poehlmann R. Portetelle D. Purnelle B. Puzos V. Ramezani Rad M. Rasmussen S.W. Remacha M.A. Revuelta J.L. Richard G.-F. Rieger M. Rodrigues-Pousada C. Rose M. Rupp T. Santos M.A. Schwager C. Sensen C. Skala J. Soares H. Sor F. Stegemann J. Tettelin H. Thierry A. Tzermia M. Urrestarazu L.A. van Dyck L. van Vliet-Reedijk J.C. Valens M. Vandenbol M. Vilela C. Vissers S. von Wettstein D. Voss H. Wiemann S. Xu G. Zimmermann J. Haasemann M. Becker I. Mewes H.-W. doi:10.1038/369371a0 1994 Nature 369 371-378 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] YKL017C Present with 1040 molecules/cell in log phase SD medium. Belongs to the DNA2/NAM7 helicase family. Uncharacterized ATP-dependent helicase YKL017C 1 683 ATP 229 236 EMBL EMBL PIR RefSeq DIP Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YKL017C KEGG CYGD SGD HCS1 LinkHub GermOnline Saccharomyces cerevisiae InterPro AAA+_ATPase_core InterPro DEAD-like_N InterPro DNA_helicase_put InterPro DNA_helicase_UvrD/REP Pfam UvrD-helicase 1 SMART AAA 1 SMART DEXDc 1 TIGRFAMs put_DNA_helic 1 SGD SGD 1994-02-01 1 78273 MNKELASKFL SSIKHEREQD IQTTSRLLTT LSIQQLVQNG LAINNIHLEN IRSGLIGKLY MELGPNLAVN DKIQRGDIKV GDIVLVRPAK TKVNTKTKPK VKKVSEDSNG EQAECSGVVY KMSDTQITIA LEESQDVIAT TFYSYSKLYI LKTTNVVTYN RMESTMRKLS EISSPIQDKI IQYLVNERPF IPNTNSFQNI KSFLNPNLND SQKTAINFAI NNDLTIIHGP PGTGKTFTLI ELIQQLLIKN PEERILICGP SNISVDTILE RLTPLVPNNL LLRIGHPARL LDSNKRHSLD ILSKKNTIVK DISQEIDKLI QENKKLKNYK QRKENWNEIK LLRKDLKKRE FKTIKDLIIQ SRIVVTTLHG SSSRELCSLY RDDPNFQLFD TLIIDEVSQA MEPQCWIPLI AHQNQFHKLV LAGDNKQLPP TIKTEDDKNV IHNLETTLFD RIIKIFPKRD MVKFLNVQYR MNQKIMEFPS HSMYNGKLLA DATVANRLLI DLPTVDATPS EDDDDTKIPL IWYDTQGDEF QETADEATIL GSKYNEGEIA IVKEHIENLR SFNVPENSIG VISPYNAQVS HLKKLIHDEL KLTDIEISTV DGFQGREKDV IILSLVRSNE KFEVGFLKEE RRLNVAMTRP RRQLVVVGNI EVLQRCGNKY LKSWSEWCEE NADVRYPNID DYL true 1994-02-01 2007-11-13 56 UTP11_YEAST UT11_YEAST YKD9_YEAST YKJ9_YEAST U3 small nucleolar RNA-associated protein 11 U3 snoRNA-associated protein 11 U three protein 11 Pallier C. Valens M. Puzos V. Fukuhara H. Cheret G. Sor F. Bolotin-Fukuhara M. 1993 Yeast 9 1149-1155 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Dujon B. Alexandraki D. Andre B. Ansorge W. Baladron V. Ballesta J.P.G. Banrevi A. Bolle P.-A. Bolotin-Fukuhara M. Bossier P. Bou G. Boyer J. Buitrago M.J. Cheret G. Colleaux L. Daignan-Fornier B. del Rey F. Dion C. Domdey H. Duesterhoeft A. Duesterhus S. Entian K.-D. Erfle H. Esteban P.F. Feldmann H. Fernandes L. Fobo G.M. Fritz C. Fukuhara H. Gabel C. Gaillon L. Garcia-Cantalejo J.M. Garcia-Ramirez J.J. Gent M.E. Ghazvini M. Goffeau A. Gonzalez A. Grothues D. Guerreiro P. Hegemann J.H. Hewitt N. Hilger F. Hollenberg C.P. Horaitis O. Indge K.J. Jacquier A. James C.M. Jauniaux J.-C. Jimenez A. Keuchel H. Kirchrath L. Kleine K. Koetter P. Legrain P. Liebl S. Louis E.J. Maia e Silva A. Marck C. Monnier A.-L. Moestl D. Mueller S. Obermaier B. Oliver S.G. Pallier C. Pascolo S. Pfeiffer F. Philippsen P. Planta R.J. Pohl F.M. Pohl T.M. Poehlmann R. Portetelle D. Purnelle B. Puzos V. Ramezani Rad M. Rasmussen S.W. Remacha M.A. Revuelta J.L. Richard G.-F. Rieger M. Rodrigues-Pousada C. Rose M. Rupp T. Santos M.A. Schwager C. Sensen C. Skala J. Soares H. Sor F. Stegemann J. Tettelin H. Thierry A. Tzermia M. Urrestarazu L.A. van Dyck L. van Vliet-Reedijk J.C. Valens M. Vandenbol M. Vilela C. Vissers S. von Wettstein D. Voss H. Wiemann S. Xu G. Zimmermann J. Haasemann M. Becker I. Mewes H.-W. doi:10.1038/369371a0 1994 Nature 369 371-378 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Dragon F. Gallagher J.E.G. Compagnone-Post P.A. Mitchell B.M. Porwancher K.A. Wehner K.A. Wormsley S. Settlage R.E. Shabanowitz J. Osheim Y. Beyer A.L. Hunt D.F. Baserga S.J. doi:10.1038/nature00769 2002 Nature 417 967-970 FUNCTION INTERACTION WITH MPP10 AND SNORNA U3 IDENTIFICATION IN SSU PROCESSOME BY MASS SPECTROMETRY SUBCELLULAR LOCATION UTP11 YKL099C YKL449 Involved in nucleolar processing of pre-18S ribosomal RNA. Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Nucleus, nucleolus. Belongs to the UTP11 family. U3 small nucleolar RNA-associated protein 11 1 256 EMBL EMBL PIR DIP IntAct Ensembl Saccharomyces cerevisiae GenomeReviews YKL099C KEGG CYGD SGD UTP11 LinkHub GermOnline Saccharomyces cerevisiae InterPro SSU_processome_Utp11 PANTHER Utp11 1 Pfam Utp11 1 PIRSF U3snoRNP11 1 UniProtKB SGD SGD SGD SGD SGD UniProtKB 1994-02-01 1 30299 MAKLVHDVQK KQHRERSQLT SRSRYGFLEK HKDYVKRAQD FHRKQSTLKV LREKAKERNP DEYYHAMHSR KTDAKGLLIS SRHGDEEDES LSMDQVKLLK TQDSNYVRTL RQIELKKLEK GAKQLMFKSS GNHTIFVDSR EKMNEFTPEK FFNTTSEMVN RSENRLTKDQ LAQDISNNRN ASSIMPKESL DKKKLKKFKQ VKQHLQRETQ LKQVQQRMDA QRELLKKGSK KKIVDSQEKF HLNGRNNGNV RFLPSI true 2006-01-10 2007-10-02 37 SYC1_YEAST Protein SYC1 Dujon B. Albermann K. Aldea M. Alexandraki D. Ansorge W. Arino J. Benes V. Bohn C. Bolotin-Fukuhara M. Bordonne R. Boyer J. Camasses A. Casamayor A. Casas C. Cheret G. Cziepluch C. Daignan-Fornier B. Dang V.-D. de Haan M. Delius H. Durand P. Fairhead C. Feldmann H. Gaillon L. Galisson F. Gamo F.-J. Gancedo C. Goffeau A. Goulding S.E. Grivell L.A. Habbig B. Hand N.J. Hani J. Hattenhorst U. Hebling U. Hernando Y. Herrero E. Heumann K. Hiesel R. Hilger F. Hofmann B. Hollenberg C.P. Hughes B. Jauniaux J.-C. Kalogeropoulos A. Katsoulou C. Kordes E. Lafuente M.J. Landt O. Louis E.J. Maarse A.C. Madania A. Mannhaupt G. Marck C. Martin R.P. Mewes H.-W. Michaux G. Paces V. Parle-McDermott A.G. Pearson B.M. Perrin A. Pettersson B. Poch O. Pohl T.M. Poirey R. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rechmann S. Schwager C. Schweizer M. Sor F. Sterky F. Tarassov I.A. Teodoru C. Tettelin H. Thierry A. Tobiasch E. Tzermia M. Uhlen M. Unseld M. Valens M. Vandenbol M. Vetter I. Vlcek C. Voet M. Volckaert G. Voss H. Wambutt R. Wedler H. Wiemann S. Winsor B. Wolfe K.H. Zollner A. Zumstein E. Kleine K. 1997 Nature 387 98-102 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Nedea E. He X. Kim M. Pootoolal J. Zhong G. Canadien V. Hughes T. Buratowski S. Moore C.L. Greenblatt J. doi:10.1074/jbc.M304454200 2003 J. Biol. Chem. 278 33000-33010 IDENTIFICATION IN THE CPF COMPLEX COMPOSITION OF THE APT COMPLEX SUBCELLULAR LOCATION IDENTIFICATION BY MASS SPECTROMETRY Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] SYC1 YOR179C Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation, including snoRNAs and snRNAs. Component of the cleavage and polyadenylation factor (CPF) complex, which is composed of at least PTI1, SYC1, SSU72, GLC7, MPE1, REF2, PFS2, PTA1, YSH1/BRR5, SWD2, CFT2/YDH1, YTH1, CFT1/YHH1, FIP1 and PAP1. Component of the APT complex, which is a subcomplex of CPF, and is composed of PTI1, SYC1, SSU72, GLC7, REF2, PTA1 and SWD2. Nucleus. Present with 1430 molecules/cell in log phase SD medium. Protein SYC1 1 188 EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YOR179C KEGG CYGD SGD SYC1 LinkHub GermOnline Saccharomyces cerevisiae SGD SGD SGD 1996-11-01 1 20866 MDLPKDKSDR THQRINLNNS GTDRTNDLYL HIVQTFGCIE TTATENATKL LMLGDVEVEI SASSVSIEWT QKSMISQTIA DSIVIMIIGL CASDKNVLSE SELKERNHNV WKIQELQNLF REQFGDSFSI DEGIGKKENV KNGSVTIGKS KATIDFSTMK LIDCNSNPLK GRVESILSIG QKLTTPLC true 2006-05-30 2007-10-02 39 TMA16_YEAST Translation machinery-associated protein 16 Poirey R. Jauniaux J.-C. doi:10.1002/(SICI)1097-0061(199704)13:5<483::AID-YEA105>3.3.CO;2-L 1997 Yeast 13 483-487 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 96604 / S288c / FY1679 Dujon B. Albermann K. Aldea M. Alexandraki D. Ansorge W. Arino J. Benes V. Bohn C. Bolotin-Fukuhara M. Bordonne R. Boyer J. Camasses A. Casamayor A. Casas C. Cheret G. Cziepluch C. Daignan-Fornier B. Dang V.-D. de Haan M. Delius H. Durand P. Fairhead C. Feldmann H. Gaillon L. Galisson F. Gamo F.-J. Gancedo C. Goffeau A. Goulding S.E. Grivell L.A. Habbig B. Hand N.J. Hani J. Hattenhorst U. Hebling U. Hernando Y. Herrero E. Heumann K. Hiesel R. Hilger F. Hofmann B. Hollenberg C.P. Hughes B. Jauniaux J.-C. Kalogeropoulos A. Katsoulou C. Kordes E. Lafuente M.J. Landt O. Louis E.J. Maarse A.C. Madania A. Mannhaupt G. Marck C. Martin R.P. Mewes H.-W. Michaux G. Paces V. Parle-McDermott A.G. Pearson B.M. Perrin A. Pettersson B. Poch O. Pohl T.M. Poirey R. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rechmann S. Schwager C. Schweizer M. Sor F. Sterky F. Tarassov I.A. Teodoru C. Tettelin H. Thierry A. Tobiasch E. Tzermia M. Uhlen M. Unseld M. Valens M. Vandenbol M. Vetter I. Vlcek C. Voet M. Volckaert G. Voss H. Wambutt R. Wedler H. Wiemann S. Winsor B. Wolfe K.H. Zollner A. Zumstein E. Kleine K. 1997 Nature 387 98-102 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Kellis M. Patterson N. Endrizzi M. Birren B.W. Lander E.S. doi:10.1038/nature01644 2003 Nature 423 241-254 SEQUENCE REVISION Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] TMA16 YOR252W Nucleus. Present with 5350 molecules/cell in log phase SD medium. 27 27 Translation machinery-associated protein 16 1 178 EMBL Frameshift. PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YOR252W KEGG CYGD SGD TMA16 LinkHub GermOnline Saccharomyces cerevisiae SGD 2006-05-30 2 20839 MPVTKSLSKL QKNLSKKGKN ITVHPKGRKY EKLVRATMRE DKIAAKKKLH QDKRVHELAR VKFMQDVVNS DTFKGQPIFD HAHTREFIQS FIERDDTELD ELKKKRRSNR PPSNRQVLLQ QRRDQELKEF KAGFLCPDLS DAKNMEFLRN WNGTFGLLNT LRLIRINDKG EQVVGGNE true 1998-07-15 2007-11-13 58 SLF1_YEAST Protein SLF1 Yu W. Farrell R.A. Stillman D.J. Winge D.R. 1996 Mol. Cell. Biol. 16 2464-2472 NUCLEOTIDE SEQUENCE [GENOMIC DNA] Jacq C. Alt-Moerbe J. Andre B. Arnold W. Bahr A. Ballesta J.P.G. Bargues M. Baron L. Becker A. Biteau N. Bloecker H. Blugeon C. Boskovic J. Brandt P. Brueckner M. Buitrago M.J. Coster F. Delaveau T. del Rey F. Dujon B. Eide L.G. Garcia-Cantalejo J.M. Goffeau A. Gomez-Peris A. Granotier C. Hanemann V. Hankeln T. Hoheisel J.D. Jaeger W. Jimenez A. Jonniaux J.-L. Kraemer C. Kuester H. Laamanen P. Legros Y. Louis E.J. Moeller-Rieker S. Monnet A. Moro M. Mueller-Auer S. Nussbaumer B. Paricio N. Paulin L. Perea J. Perez-Alonso M. Perez-Ortin J.E. Pohl T.M. Prydz H. Purnelle B. Rasmussen S.W. Remacha M.A. Revuelta J.L. Rieger M. Salom D. Saluz H.P. Saiz J.E. Saren A.-M. Schaefer M. Scharfe M. Schmidt E.R. Schneider C. Scholler P. Schwarz S. Soler-Mira A. Urrestarazu L.A. Verhasselt P. Vissers S. Voet M. Volckaert G. Wagner G. Wambutt R. Wedler E. Wedler H. Woelfl S. Harris D.E. Bowman S. Brown D. Churcher C.M. Connor R. Dedman K. Gentles S. Hamlin N. Hunt S. Jones L. McDonald S. Murphy L.D. Niblett D. Odell C. Oliver K. Rajandream M.A. Richards C. Shore L. Walsh S.V. Barrell B.G. Dietrich F.S. Mulligan J.T. Allen E. Araujo R. Aviles E. Berno A. Carpenter J. Chen E. Cherry J.M. Chung E. Duncan M. Hunicke-Smith S. Hyman R.W. Komp C. Lashkari D. Lew H. Lin D. Mosedale D. Nakahara K. Namath A. Oefner P. Oh C. Petel F.X. Roberts D. Schramm S. Schroeder M. Shogren T. Shroff N. Winant A. Yelton M.A. Botstein D. Davis R.W. Johnston M. Andrews S. Brinkman R. Cooper J. Ding H. Du Z. Favello A. Fulton L. Gattung S. Greco T. Hallsworth K. Hawkins J. Hillier L.W. Jier M. Johnson D. Johnston L. Kirsten J. Kucaba T. Langston Y. Latreille P. Le T. Mardis E. Menezes S. Miller N. Nhan M. Pauley A. Peluso D. Rifkin L. Riles L. Taich A. Trevaskis E. Vignati D. Wilcox L. Wohldman P. Vaudin M. Wilson R. Waterston R. Albermann K. Hani J. Heumann K. Kleine K. Mewes H.-W. Zollner A. Zaccaria P. 1997 Nature 387 75-78 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Gruhler A. Olsen J.V. Mohammed S. Mortensen P. Faergeman N.J. Mann M. Jensen O.N. doi:10.1074/mcp.M400219-MCP200 2005 Mol. Cell. Proteomics 4 310-327 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42 MASS SPECTROMETRY SLF1 YDR515W D9719.20 Regulates the copper-dependent mineralization of copper sulfide complexes on the cell surface in cells cultured in medium containing copper salts. Present with 861 molecules/cell in log phase SD medium. Contains 1 HTH La-type RNA-binding domain. Protein SLF1 1 447 HTH La-type RNA-binding 265 368 Phosphoserine 42 42 EMBL EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YDR515W KEGG CYGD SGD SLF1 LinkHub GermOnline Saccharomyces cerevisiae InterPro Lupus_La InterPro Lupus_La_RNA_bd InterPro Wing_hlx_DNA_bd Gene3D Wing_hlx_DNA_bd 1 Pfam La 1 PRINTS LUPUSLA SMART LA 1 PROSITE HTH_LA 1 SGD SGD SGD SGD SGD 1996-11-01 1 50943 MSSQNLNDNP KNTSSAAEDK KKQTSSLKLA PIPTTSPWKS SSPDSNTVIP VEELRDISKT AKPSKNGSGS IKLTSNTKWT PITPSVIISG SKDTNSKSGK NSKNSKTNKK MKKRGKYNND INKKDFNGQT NSTSEISNVS NLESKPLDAN AKVNIHSSSG ATANGNIKRI TNNNNSTNGR QSRNYQNRNG KTRYNNNSRH SQAANNAISF PNNYQARPEY IPNASHWLNN NSRNSYKQLS YFRQQQYYNN INYQQQLQTP YYYSMEPIFK SIESIKNQIE FYFSEENLKT DEFLRSKFKK ANDGFIPMSL IGKFYRMVNL SLGGDPNLIL ASMREVLQHK ETNHLEIALG SIEGAQKNMA DDFNPLENYF IRRENWAEYA MESNFDENDD ETEKYNIEKL LGPNDLDNYS YMGYPNFFPS NENGKKSQSY DQGEISRQFE QNLQIND true 2005-03-15 2007-10-02 45 PSF3_YEAST DNA replication complex GINS protein PSF3 Partner of Sld five 3 Casamayor A. Aldea M. Casas C. Herrero E. Gamo F.-J. Lafuente M.J. Gancedo C. Arino J. 1995 Yeast 11 1281-1288 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 96604 / S288c / FY1679 Dujon B. Albermann K. Aldea M. Alexandraki D. Ansorge W. Arino J. Benes V. Bohn C. Bolotin-Fukuhara M. Bordonne R. Boyer J. Camasses A. Casamayor A. Casas C. Cheret G. Cziepluch C. Daignan-Fornier B. Dang V.-D. de Haan M. Delius H. Durand P. Fairhead C. Feldmann H. Gaillon L. Galisson F. Gamo F.-J. Gancedo C. Goffeau A. Goulding S.E. Grivell L.A. Habbig B. Hand N.J. Hani J. Hattenhorst U. Hebling U. Hernando Y. Herrero E. Heumann K. Hiesel R. Hilger F. Hofmann B. Hollenberg C.P. Hughes B. Jauniaux J.-C. Kalogeropoulos A. Katsoulou C. Kordes E. Lafuente M.J. Landt O. Louis E.J. Maarse A.C. Madania A. Mannhaupt G. Marck C. Martin R.P. Mewes H.-W. Michaux G. Paces V. Parle-McDermott A.G. Pearson B.M. Perrin A. Pettersson B. Poch O. Pohl T.M. Poirey R. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rechmann S. Schwager C. Schweizer M. Sor F. Sterky F. Tarassov I.A. Teodoru C. Tettelin H. Thierry A. Tobiasch E. Tzermia M. Uhlen M. Unseld M. Valens M. Vandenbol M. Vetter I. Vlcek C. Voet M. Volckaert G. Voss H. Wambutt R. Wedler H. Wiemann S. Winsor B. Wolfe K.H. Zollner A. Zumstein E. Kleine K. 1997 Nature 387 98-102 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Hu Y. Rolfs A. Bhullar B. Murthy T.V.S. Zhu C. Berger M.F. Camargo A.A. Kelley F. McCarron S. Jepson D. Richardson A. Raphael J. Moreira D. Taycher E. Zuo D. Mohr S. Kane M.F. Williamson J. Simpson A.J.G. Bulyk M.L. Harlow E. Marsischky G. Kolodner R.D. LaBaer J. doi:10.1101/gr.6037607 2007 Genome Res. 17 536-543 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Kellis M. Patterson N. Endrizzi M. Birren B.W. Lander E.S. doi:10.1038/nature01644 2003 Nature 423 241-254 IDENTIFICATION OF PROBABLE INITIATION SITE Takayama Y. Kamimura Y. Okawa M. Muramatsu S. Sugino A. Araki H. doi:10.1101/gad.1065903 2003 Genes Dev. 17 1153-1165 FUNCTION AND COMPOSITION OF THE GINS COMPLEX SUBCELLULAR LOCATION Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] PSF3 YOL146W Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery. Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3. Nucleus. Present with 2205 molecules/cell in log phase SD medium. Belongs to the PSF3 family. DNA replication complex GINS protein PSF3 1 194 EMBL Different initiation. EMBL Different initiation. EMBL Different initiation. PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YOL146W KEGG CYGD SGD PSF3 LinkHub GermOnline Saccharomyces cerevisiae InterPro GINS_Psf3 PANTHER GINS_Psf3 1 Pfam Psf3 1 SGD SGD SGD 2005-03-15 2 21952 MGYYDIDDVL ADGTEFPCKF QYDIPGLGYL ENNPGRPITK NTKLSLPLWL ARILAIVGGD EALVDEEPVP FVELLPPDMF STKVMNAIKT DPVALDLHSI NSHFFSLAIK WIMLFSEKEL ANVVSELLLQ RAQELNHHAS SLSIDLNADS TGKNSANTNI ATSTFLLKLE EMEKEIYKKS HESYKDTKRW MFKK true 2006-05-16 2007-11-13 52 MDY2_YEAST Ubiquitin-like protein MDY2 Mating-deficient protein 2 Translation machinery-associated protein 24 Vandenbol M. Durand P. Portetelle D. Hilger F. 1995 Yeast 11 1069-1075 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 96604 / S288c / FY1679 Dujon B. Albermann K. Aldea M. Alexandraki D. Ansorge W. Arino J. Benes V. Bohn C. Bolotin-Fukuhara M. Bordonne R. Boyer J. Camasses A. Casamayor A. Casas C. Cheret G. Cziepluch C. Daignan-Fornier B. Dang V.-D. de Haan M. Delius H. Durand P. Fairhead C. Feldmann H. Gaillon L. Galisson F. Gamo F.-J. Gancedo C. Goffeau A. Goulding S.E. Grivell L.A. Habbig B. Hand N.J. Hani J. Hattenhorst U. Hebling U. Hernando Y. Herrero E. Heumann K. Hiesel R. Hilger F. Hofmann B. Hollenberg C.P. Hughes B. Jauniaux J.-C. Kalogeropoulos A. Katsoulou C. Kordes E. Lafuente M.J. Landt O. Louis E.J. Maarse A.C. Madania A. Mannhaupt G. Marck C. Martin R.P. Mewes H.-W. Michaux G. Paces V. Parle-McDermott A.G. Pearson B.M. Perrin A. Pettersson B. Poch O. Pohl T.M. Poirey R. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rechmann S. Schwager C. Schweizer M. Sor F. Sterky F. Tarassov I.A. Teodoru C. Tettelin H. Thierry A. Tobiasch E. Tzermia M. Uhlen M. Unseld M. Valens M. Vandenbol M. Vetter I. Vlcek C. Voet M. Volckaert G. Voss H. Wambutt R. Wedler H. Wiemann S. Winsor B. Wolfe K.H. Zollner A. Zumstein E. Kleine K. 1997 Nature 387 98-102 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Iwanejko L. Smith K.N. Loeillet S. Nicolas A. Fabre F. doi:10.1002/(SICI)1097-0061(199910)15:14<1529::AID-YEA457>3.3.CO;2-P 1999 Yeast 15 1529-1539 FUNCTION Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Hu Z. Potthoff B. Hollenberg C.P. Ramezani-Rad M. doi:10.1242/jcs.02754 2006 J. Cell Sci. 119 326-338 FUNCTION SUBCELLULAR LOCATION MDY2 TMA24 YOL111C Required for efficient mating. Involved in the production of alpha-factor, the KAR9 and TUB1 location to the shmoo tip and nuclear migration into pheromone-induced shmoos. Cytoplasm. Nucleus. Present with 6510 molecules/cell in log phase SD medium. Contains 1 ubiquitin-like domain. Ubiquitin-like protein MDY2 1 212 Ubiquitin-like 74 152 false 1 CIA1 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YOL111C KEGG CYGD SGD MDY2 LinkHub GermOnline Saccharomyces cerevisiae InterPro Ubiquitin Pfam ubiquitin 1 SMART UBQ 1 PROSITE UBIQUITIN_1 true PROSITE UBIQUITIN_2 1 SGD SGD IntAct SGD 1996-11-01 1 23732 MSTSASGPEH EFVSKFLTLA TLTEPKLPKS YTKPLKDVTN LGVPLPTLKY KYKQNRAKKL KLHQDQQGQD NAAVHLTLKK IQAPKFSIEH DFSPSDTILQ IKQHLISEEK ASHISEIKLL LKGKVLHDNL FLSDLKVTPA NSTITVMIKP NPTISKEPEA EKSTNSPAPA PPQELTVPWD DIEALLKNNF ENDQAAVRQV MERLQKGWSL AK true 2006-07-11 2007-11-13 48 UTP23_YEAST rRNA-processing protein UTP23 U3-associated protein 23 Sterky F. Holmberg A. Pettersson B. Uhlen M. doi:10.1002/(SICI)1097-0061(199609)12:10B<1091::AID-YEA22>3.3.CO;2-9 1996 Yeast 12 1091-1095 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 96604 / S288c / FY1679 Dujon B. Albermann K. Aldea M. Alexandraki D. Ansorge W. Arino J. Benes V. Bohn C. Bolotin-Fukuhara M. Bordonne R. Boyer J. Camasses A. Casamayor A. Casas C. Cheret G. Cziepluch C. Daignan-Fornier B. Dang V.-D. de Haan M. Delius H. Durand P. Fairhead C. Feldmann H. Gaillon L. Galisson F. Gamo F.-J. Gancedo C. Goffeau A. Goulding S.E. Grivell L.A. Habbig B. Hand N.J. Hani J. Hattenhorst U. Hebling U. Hernando Y. Herrero E. Heumann K. Hiesel R. Hilger F. Hofmann B. Hollenberg C.P. Hughes B. Jauniaux J.-C. Kalogeropoulos A. Katsoulou C. Kordes E. Lafuente M.J. Landt O. Louis E.J. Maarse A.C. Madania A. Mannhaupt G. Marck C. Martin R.P. Mewes H.-W. Michaux G. Paces V. Parle-McDermott A.G. Pearson B.M. Perrin A. Pettersson B. Poch O. Pohl T.M. Poirey R. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rechmann S. Schwager C. Schweizer M. Sor F. Sterky F. Tarassov I.A. Teodoru C. Tettelin H. Thierry A. Tobiasch E. Tzermia M. Uhlen M. Unseld M. Valens M. Vandenbol M. Vetter I. Vlcek C. Voet M. Volckaert G. Voss H. Wambutt R. Wedler H. Wiemann S. Winsor B. Wolfe K.H. Zollner A. Zumstein E. Kleine K. 1997 Nature 387 98-102 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Wu L.F. Hughes T.R. Davierwala A.P. Robinson M.D. Stoughton R. Altschuler S.J. doi:10.1038/ng906 2002 Nat. Genet. 31 255-265 FUNCTION Hazbun T.R. Malmstroem L. Anderson S. Graczyk B.J. Fox B. Riffle M. Sundin B.A. Aranda J.D. McDonald W.H. Chiu C.-H. Snydsman B.E. Bradley P. Muller E.G.D. Fields S. Baker D. Yates J.R. III Davis T.N. doi:10.1016/S1097-2765(03)00476-3 2003 Mol. Cell 12 1353-1365 SUBCELLULAR LOCATION Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] UTP23 YOR004W Involved in rRNA-processing and ribosome biogenesis. Mitochondrion. Nucleus, nucleolus. Present with 6960 molecules/cell in log phase SD medium. Belongs to the UTP23 family. rRNA-processing protein UTP23 1 254 Lys-rich 188 239 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YOR004W KEGG CYGD SGD UTP23 LinkHub GermOnline Saccharomyces cerevisiae InterPro DUF652 PANTHER DUF652 1 Pfam Fcf1 1 SGD SGD SGD 1996-11-01 1 28801 MRQKRAKSYR KQLLVYSHTF KFREPYQVLV DNQLVLECNN SNFNLPSGLK RTLQADVKVM ITQCCIQALY ETRNDGAINL AKQFERRRCN HSFKDPKSPA ECIESVVNIS GANKHRYVVA SQDIDLRRKL RTVPGVPLIH LTRSVMVMEP LSTASAKASK ITEEQKLYKG LNDPNIEKLQ ESGDGSGKES ITKKRKLGPK APNPLSVKKK KKVNSPSDEV KDKEDTSKEK KKRRRRKHKS NTNVPVSNGT TAAQ true 2006-07-11 2007-10-02 38 HRT3_YEAST F-box protein HRT3 High level expression reduces Ty3 transposition protein 3 Johnston M. Hillier L.W. Riles L. Albermann K. Andre B. Ansorge W. Benes V. Brueckner M. Delius H. Dubois E. Duesterhoeft A. Entian K.-D. Floeth M. Goffeau A. Hebling U. Heumann K. Heuss-Neitzel D. Hilbert H. Hilger F. Kleine K. Koetter P. Louis E.J. Messenguy F. Mewes H.-W. Miosga T. Moestl D. Mueller-Auer S. Nentwich U. Obermaier B. Piravandi E. Pohl T.M. Portetelle D. Purnelle B. Rechmann S. Rieger M. Rinke M. Rose M. Scharfe M. Scherens B. Scholler P. Schwager C. Schwarz S. Underwood A.P. Urrestarazu L.A. Vandenbol M. Verhasselt P. Vierendeels F. Voet M. Volckaert G. Voss H. Wambutt R. Wedler E. Wedler H. Zimmermann F.K. Zollner A. Hani J. Hoheisel J.D. 1997 Nature 387 87-90 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Seol J.H. Shevchenko A. Shevchenko A.' Deshaies R.J. doi:10.1038/35070067 2001 Nat. Cell Biol. 3 384-391 INTERACTION WITH SKP1 MASS SPECTROMETRY Kus B.M. Caldon C.E. Andorn-Broza R. Edwards A.M. doi:10.1002/prot.10620 2004 Proteins 54 455-467 INTERACTION WITH SKP1 IDENTIFICATION IN A SCF COMPLEX FUNCTION HRT3 YLR097C Probable F-box protein component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Protein degradation; protein ubiquitinylation. Interacts with SKP1. May form a SCF complex with CDC53, RBX1 and SKP1. Contains 1 F-box domain. Contains 1 TPR repeat. F-box protein HRT3 1 344 TPR 14 47 F-box 98 148 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YLR097C KEGG CYGD SGD HRT3 LinkHub GermOnline Saccharomyces cerevisiae InterPro F-box Pfam F-box 1 PROSITE FBOX true PROSITE TPR true PROSITE TPR_REGION true SGD SGD 1996-11-01 1 40475 MIVDYEKDPR AKEAIAIWEK GVLKEKDGSM SDAINFYRSA LKIHDNVESL YRKKILDEWM LHKKLSGLSM TTDAPDEQNE TGKDDLSVEE NAELQPCWIL EILPDDILLR IIKKVILMSG ESWVNLSMTC STFSKLCFHD SVPFKTFAKY IYSKQIYDKM AMDLNGITDI NTFEKEIWRG DDYRMLRERP YIKFEGVYIS VVNYVRYGSN AESSLSLLKP VHMITYYRYF RFYENGQCLR LLSTDEPSAV VKHFSKENKP RHSHMCYWSL GFDYDFGHLK ITRSDEKYTF IEEFQIKNQG NKRYQRLKWL SSIVVDKEGN ASNCSLRNEK SFFFSRVKSF KDPG true 2005-11-22 2007-11-13 43 CSN10_YEAST COP9 signalosome complex subunit 10 Vandenbol M. Durand P. Portetelle D. Hilger F. 1995 Yeast 11 1069-1075 NUCLEOTIDE SEQUENCE [GENOMIC DNA] Dujon B. Albermann K. Aldea M. Alexandraki D. Ansorge W. Arino J. Benes V. Bohn C. Bolotin-Fukuhara M. Bordonne R. Boyer J. Camasses A. Casamayor A. Casas C. Cheret G. Cziepluch C. Daignan-Fornier B. Dang V.-D. de Haan M. Delius H. Durand P. Fairhead C. Feldmann H. Gaillon L. Galisson F. Gamo F.-J. Gancedo C. Goffeau A. Goulding S.E. Grivell L.A. Habbig B. Hand N.J. Hani J. Hattenhorst U. Hebling U. Hernando Y. Herrero E. Heumann K. Hiesel R. Hilger F. Hofmann B. Hollenberg C.P. Hughes B. Jauniaux J.-C. Kalogeropoulos A. Katsoulou C. Kordes E. Lafuente M.J. Landt O. Louis E.J. Maarse A.C. Madania A. Mannhaupt G. Marck C. Martin R.P. Mewes H.-W. Michaux G. Paces V. Parle-McDermott A.G. Pearson B.M. Perrin A. Pettersson B. Poch O. Pohl T.M. Poirey R. Portetelle D. Pujol A. Purnelle B. Ramezani Rad M. Rechmann S. Schwager C. Schweizer M. Sor F. Sterky F. Tarassov I.A. Teodoru C. Tettelin H. Thierry A. Tobiasch E. Tzermia M. Uhlen M. Unseld M. Valens M. Vandenbol M. Vetter I. Vlcek C. Voet M. Volckaert G. Voss H. Wambutt R. Wedler H. Wiemann S. Winsor B. Wolfe K.H. Zollner A. Zumstein E. Kleine K. 1997 Nature 387 98-102 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 96604 / S288c / FY1679 Wee S. Hetfeld B. Dubiel W. Wolf D.A. doi:10.1186/1471-2156-3-15 2002 BMC Genet. 3 15 FUNCTION OF THE COP9 SIGNALOSOME COMPLEX Maytal-Kivity V. Piran R. Pick E. Hofmann K. Glickman M.H. doi:10.1093/embo-reports/kvf235 2002 EMBO Rep. 3 1215-1221 INTERACTION WITH CSN12 IDENTIFICATION IN THE COP9 SIGNALOSOME COMPLEX FUNCTION OF THE COP9 SIGNALOSOME COMPLEX Gavin A.-C. Boesche M. Krause R. Grandi P. Marzioch M. Bauer A. Schultz J. Rick J.M. Michon A.-M. Cruciat C.-M. Remor M. Hoefert C. Schelder M. Brajenovic M. Ruffner H. Merino A. Klein K. Hudak M. Dickson D. Rudi T. Gnau V. Bauch A. Bastuck S. Huhse B. Leutwein C. Heurtier M.-A. Copley R.R. Edelmann A. Querfurth E. Rybin V. Drewes G. Raida M. Bouwmeester T. Bork P. Seraphin B. Kuster B. Neubauer G. Superti-Furga G. doi:10.1038/415141a 2002 Nature 415 141-147 INTERACTION WITH RRI1/CSN5 IDENTIFICATION BY MASS SPECTROMETRY Maytal-Kivity V. Pick E. Piran R. Hofmann K. Glickman M.H. doi:10.1016/S1357-2725(02)00378-3 2003 Int. J. Biochem. Cell Biol. 35 706-715 INTERACTION WITH CSN12 IDENTIFICATION IN THE COP9 SIGNALOSOME COMPLEX Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] RRI2 CSN10 YOL117W Component of the COP9 signalosome (CSN) complex that is required for cleaving the ubiquitin-like protein RUB1/NEDD8 from neddylated cullin CDC53, a SCF ubiquitin-ligase subunit. The complex is involved in the regulation of the mating pheromone response. Component of the COP9 signalosome (CSN) complex, composed of at least RRI1/CSN5, CSN9, RRI2/CSN10, PCI8/CSN11, CSN12 and CSI1. In the complex, it probably interacts directly with CSN12. Cytoplasm (Probable). Nucleus (Probable). Present with 1320 molecules/cell in log phase SD medium. Contains 1 PCI domain. COP9 signalosome complex subunit 10 1 645 PCI 430 540 false 2 CSN12 EMBL EMBL PIR RefSeq DIP IntAct Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YOL117W KEGG CYGD SGD RRI2 LinkHub GermOnline Saccharomyces cerevisiae SGD IntAct SGD SGD 1996-11-01 1 76388 MSDEDNNYDD FMLSDDEGME SIEMEEETDD EDKQNIEINE DNSQDDQDRG AARHKQHEQG TFEKHDRVED ICERIFEQGQ ALKEDERYKE ARDLFLKIYY KEEFSSDESI ERLMTWKFKS LIEILRLRAL QLYFQKNGAQ DLVLQILEDT ATMSVFLQRI DFQIDGNIFE LLSDTFEVLA PKWERVFLFD IEKVDRENMI CKIDFQKNFM DQFQWILRKP GKDCKLQNLQ RIIRKKIFIA VVWYQRLTMG NVFTPEISSQ IEILVKDNEC SSFEENNDLE SVSMLLQYYI LEYMNTARIN NRRLFKKCID FFEMLISKSL TFSQESGLMV ILYTSKIVFI LDSDSENDLS FALMRYYDRK EELKNMFLYI LKHLEEMGKL RERDITSLFH KFILSGFIFT SMILEAISTD KINPFGFEQV KIALGSPIVN VLEDVYRCFA QLELRQLNAS ISLIPELSVV LSGIIQDIYY LAQTLKLWRK IARLYSCISI SDIISMLQIS DDNEMTRDDL LTILMRSIMK NRSVVYFKLD LTSDLVYFGD ENKVMLPRCS KEEFRLMISP KDEETTEKAR LIDFEYVNDV AIYNNPTRIR TKSSKEFFNT LRKSRETVKL PRVSNQSNED TFLPSYMKFS NKYLELCKLA SNNLE true 2006-03-21 2007-10-02 46 HIF1_YEAST HAT1-interacting factor 1 Purnelle B. Goffeau A. doi:10.1002/(SICI)1097-0061(199702)13:2<183::AID-YEA65>3.3.CO;2-M 1997 Yeast 13 183-188 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 204508 / S288c Johnston M. Hillier L.W. Riles L. Albermann K. Andre B. Ansorge W. Benes V. Brueckner M. Delius H. Dubois E. Duesterhoeft A. Entian K.-D. Floeth M. Goffeau A. Hebling U. Heumann K. Heuss-Neitzel D. Hilbert H. Hilger F. Kleine K. Koetter P. Louis E.J. Messenguy F. Mewes H.-W. Miosga T. Moestl D. Mueller-Auer S. Nentwich U. Obermaier B. Piravandi E. Pohl T.M. Portetelle D. Purnelle B. Rechmann S. Rieger M. Rinke M. Rose M. Scharfe M. Scherens B. Scholler P. Schwager C. Schwarz S. Underwood A.P. Urrestarazu L.A. Vandenbol M. Verhasselt P. Vierendeels F. Voet M. Volckaert G. Voss H. Wambutt R. Wedler E. Wedler H. Zimmermann F.K. Zollner A. Hani J. Hoheisel J.D. 1997 Nature 387 87-90 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204511 / S288c / AB972 Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Poveda A. Pamblanco M. Tafrov S. Tordera V. Sternglanz R. Sendra R. doi:10.1074/jbc.M314228200 2004 J. Biol. Chem. 279 16033-16043 IDENTIFICATION IN THE NUCLEAR HAT-B COMPLEX FUNCTION OF THE HAT-B COMPLEX INTERACTION WITH HISTONE H4 SUBCELLULAR LOCATION Ai X. Parthun M.R. doi:10.1016/S1097-2765(04)00184-4 2004 Mol. Cell 14 195-205 FUNCTION IDENTIFICATION IN THE NUCLEAR HAT-B COMPLEX MASS SPECTROMETRY INTERACTION WITH HISTONES H3 AND H4 SUBCELLULAR LOCATION HIF1 YLL022C L1205 Histone H3 and H4 specific chaperone component of the nuclear histone acetyltransferase B (HAT-B) complex. Involved in chromatin assembly and telomere silencing. Component of the nuclear histone acetyltransferase B (HAT-B) complex composed of at least HAT1, HAT2 and HIF1. Interacts with histones H3 and H4 in a HAT1/HAT2 dependent manner. Nucleus. Present with 4550 molecules/cell in log phase SD medium. Contains 2 TPR repeats. HAT1-interacting factor 1 1 385 TPR 1 186 220 TPR 2 229 262 Glu-rich 97 184 EMBL EMBL PIR RefSeq DIP IntAct PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YLL022C KEGG CYGD SGD HIF1 LinkHub GermOnline Saccharomyces cerevisiae PROSITE TPR true PROSITE TPR_REGION true SGD SGD SGD SGD SGD 1996-11-01 1 43428 MKLRAEDVLA NGTSRHKVQI DMERQVQIAK DLLAQKKFLE AAKRCQQTLD SLPKDGLLPD PELFTIFAQA VYNMEVQNSG NLFGDALLAG DDGSGSESES EPESDVSNGE EGNENGQTEI PNSRMFQFDQ EEEDLTGDVD SGDSEDSGEG SEEEEENVEK EEERLALHEL ANFSPANEHD DEIEDVSQLR KSGFHIYFEN DLYENALDLL AQALMLLGRP TADGQSLTEN SRLRIGDVYI LMGDIEREAE MFSRAIHHYL KALGYYKTLK PAEQVTEKVI QAEFLVCDAL RWVDQVPAKD KLKRFKHAKA LLEKHMTTRP KDSELQQARL AQIQDDIDEV QENQQHGSKR PLSQPTTSIG FPALEKPLGD FNDLSQLVKK KPRRH true 2006-06-27 2007-11-13 42 TMA17_YEAST Translation machinery-associated protein 17 Boskovic J. Soler-Mira A. Garcia-Cantalejo J.M. Ballesta J.P.G. Jimenez A. Remacha M.A. doi:10.1002/(SICI)1097-0061(199610)12:13<1377::AID-YEA35>3.0.CO;2-R 1996 Yeast 12 1377-1384 NUCLEOTIDE SEQUENCE [GENOMIC DNA] ATCC 96604 / S288c / FY1679 Jacq C. Alt-Moerbe J. Andre B. Arnold W. Bahr A. Ballesta J.P.G. Bargues M. Baron L. Becker A. Biteau N. Bloecker H. Blugeon C. Boskovic J. Brandt P. Brueckner M. Buitrago M.J. Coster F. Delaveau T. del Rey F. Dujon B. Eide L.G. Garcia-Cantalejo J.M. Goffeau A. Gomez-Peris A. Granotier C. Hanemann V. Hankeln T. Hoheisel J.D. Jaeger W. Jimenez A. Jonniaux J.-L. Kraemer C. Kuester H. Laamanen P. Legros Y. Louis E.J. Moeller-Rieker S. Monnet A. Moro M. Mueller-Auer S. Nussbaumer B. Paricio N. Paulin L. Perea J. Perez-Alonso M. Perez-Ortin J.E. Pohl T.M. Prydz H. Purnelle B. Rasmussen S.W. Remacha M.A. Revuelta J.L. Rieger M. Salom D. Saluz H.P. Saiz J.E. Saren A.-M. Schaefer M. Scharfe M. Schmidt E.R. Schneider C. Scholler P. Schwarz S. Soler-Mira A. Urrestarazu L.A. Verhasselt P. Vissers S. Voet M. Volckaert G. Wagner G. Wambutt R. Wedler E. Wedler H. Woelfl S. Harris D.E. Bowman S. Brown D. Churcher C.M. Connor R. Dedman K. Gentles S. Hamlin N. Hunt S. Jones L. McDonald S. Murphy L.D. Niblett D. Odell C. Oliver K. Rajandream M.A. Richards C. Shore L. Walsh S.V. Barrell B.G. Dietrich F.S. Mulligan J.T. Allen E. Araujo R. Aviles E. Berno A. Carpenter J. Chen E. Cherry J.M. Chung E. Duncan M. Hunicke-Smith S. Hyman R.W. Komp C. Lashkari D. Lew H. Lin D. Mosedale D. Nakahara K. Namath A. Oefner P. Oh C. Petel F.X. Roberts D. Schramm S. Schroeder M. Shogren T. Shroff N. Winant A. Yelton M.A. Botstein D. Davis R.W. Johnston M. Andrews S. Brinkman R. Cooper J. Ding H. Du Z. Favello A. Fulton L. Gattung S. Greco T. Hallsworth K. Hawkins J. Hillier L.W. Jier M. Johnson D. Johnston L. Kirsten J. Kucaba T. Langston Y. Latreille P. Le T. Mardis E. Menezes S. Miller N. Nhan M. Pauley A. Peluso D. Rifkin L. Riles L. Taich A. Trevaskis E. Vignati D. Wilcox L. Wohldman P. Vaudin M. Wilson R. Waterston R. Albermann K. Hani J. Heumann K. Kleine K. Mewes H.-W. Zollner A. Zaccaria P. 1997 Nature 387 75-78 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] ATCC 204508 / S288c Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Fleischer T.C. Weaver C.M. McAfee K.J. Jennings J.L. Link A.J. doi:10.1101/gad.1422006 2006 Genes Dev. 20 1294-1307 IDENTIFICATION BY MASS SPECTROMETRY SUBUNIT Li X. Gerber S.A. Rudner A.D. Beausoleil S.A. Haas W. Villen J. Elias J.E. Gygi S.P. doi:10.1021/pr060559j 2007 J. Proteome Res. 6 1190-1197 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-68 MASS SPECTROMETRY Smolka M.B. Albuquerque C.P. Chen S.H. Zhou H. doi:10.1073/pnas.0701622104 2007 Proc. Natl. Acad. Sci. U.S.A. 104 10364-10369 PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-68 MASS SPECTROMETRY TMA17 YDL110C D2320 Interacts with the 40S and 60S ribosomal subunits. Cytoplasm. Nucleus. Present with 2110 molecules/cell in log phase SD medium. Translation machinery-associated protein 17 1 150 Phosphoserine 68 68 EMBL EMBL PIR RefSeq DIP PeptideAtlas Ensembl Saccharomyces cerevisiae GeneID GenomeReviews YDL110C KEGG CYGD SGD TMA17 LinkHub GermOnline Saccharomyces cerevisiae SGD SGD 1996-11-01 1 16771 MCSAGGIRRP IQIEEFKTAI SGMSDMELAQ IKTEIENSIN HLQRSNARLG KYIAKLEGAD DRLEADDSDD LENIDSGDLA LYKDSVRENE IVLNNYNERV DALEQETVYR KTGHGKSKHE VEAKDNTNKG PDVDMDNSNV DVVTPNSIFI true 1986-07-21 2007-12-04 83 RL44_YEAST RL27_YEAST 60S ribosomal protein L42 L41 YL27 YP44 Maintenance of killer protein 18 Kawai S. Murao S. Mochizuki M. Shibuya I. Yano K. Takagi M. 1992 J. Bacteriol. 174 254-262 NUCLEOTIDE SEQUENCE [GENOMIC DNA] (RPL42A AND RPL42B) Nasr F. Becam A.-M. Herbert C.J. doi:10.1002/(SICI)1097-0061(199602)12:2<169::AID-YEA894>3.0.CO;2-B 1996 Yeast 12 169-175 NUCLEOTIDE SEQUENCE [GENOMIC DNA] (RPL42A) ATCC 96604 / S288c / FY1679 Philippsen P. Kleine K. Poehlmann R. Duesterhoeft A. Hamberg K. Hegemann J.H. Obermaier B. Urrestarazu L.A. Aert R. Albermann K. Altmann R. Andre B. Baladron V. Ballesta J.P.G. Becam A.-M. Beinhauer J.D. Boskovic J. Buitrago M.J. Bussereau F. Coster F. Crouzet M. D'Angelo M. Dal Pero F. De Antoni A. del Rey F. Doignon F. Domdey H. Dubois E. Fiedler T.A. Fleig U. Floeth M. Fritz C. Gaillardin C. Garcia-Cantalejo J.M. Glansdorff N. Goffeau A. Gueldener U. Herbert C.J. Heumann K. Heuss-Neitzel D. Hilbert H. Hinni K. Iraqui Houssaini I. Jacquet M. Jimenez A. Jonniaux J.-L. Karpfinger-Hartl L. Lanfranchi G. Lepingle A. Levesque H. Lyck R. Maftahi M. Mallet L. Maurer C.T.C. Messenguy F. Mewes H.-W. Moestl D. Nasr F. Nicaud J.-M. Niedenthal R.K. Pandolfo D. Pierard A. Piravandi E. Planta R.J. Pohl T.M. Purnelle B. Rebischung C. Remacha M.A. Revuelta J.L. Rinke M. Saiz J.E. Sartorello F. Scherens B. Sen-Gupta M. Soler-Mira A. Urbanus J.H.M. Valle G. Van Dyck L. Verhasselt P. Vierendeels F. Vissers S. Voet M. Volckaert G. Wach A. Wambutt R. Wedler H. Zollner A. Hani J. 1997 Nature 387 93-98 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (RPL42A) ATCC 204508 / S288c Johnston M. Andrews S. Brinkman R. Cooper J. Ding H. Dover J. Du Z. Favello A. Fulton L. Gattung S. Geisel C. Kirsten J. Kucaba T. Hillier L.W. Jier M. Johnston L. Langston Y. Latreille P. Louis E.J. Macri C. Mardis E. Menezes S. Mouser L. Nhan M. Rifkin L. Riles L. St Peter H. Trevaskis E. Vaughan K. Vignati D. Wilcox L. Wohldman P. Waterston R. Wilson R. Vaudin M. 1994 Science 265 2077-2082 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (RPL42B) ATCC 204511 / S288c / AB972 Itoh T. Wittmann-Liebold B. doi:10.1016/0014-5793(78)80447-5 1978 FEBS Lett. 96 399-402 PROTEIN SEQUENCE OF 2-106 Carroll K. Wickner R.B. 1995 J. Bacteriol. 177 2887-2891 IDENTIFICATION AS MAK18 Planta R.J. Mager W.H. doi:10.1002/(SICI)1097-0061(19980330)14:5<471::AID-YEA241>3.0.CO;2-U 1998 Yeast 14 471-477 NOMENCLATURE SUBUNIT Huh W.-K. Falvo J.V. Gerke L.C. Carroll A.S. Howson R.W. Weissman J.S. O'Shea E.K. doi:10.1038/nature02026 2003 Nature 425 686-691 SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS] Ghaemmaghami S. Huh W.-K. Bower K. Howson R.W. Belle A. Dephoure N. O'Shea E.K. Weissman J.S. doi:10.1038/nature02046 2003 Nature 425 737-741 LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS] Spahn C.M.T. Beckmann R. Eswar N. Penczek P.A. Sali A. Blobel G. Frank J. doi:10.1016/S0092-8674(01)00539-6 2001 Cell 107 373-386 3D-STRUCTURE MODELING OF 2-92 ELECTRON MICROSCOPY Spahn C.M.T. Gomez-Lorenzo M.G. Grassucci R.A. Joergensen R. Andersen G.R. Beckmann R. Penczek P.A. Ballesta J.P.G. Frank J. doi:10.1038/sj.emboj.7600102 2004 EMBO J. 23 1008-1019 3D-STRUCTURE MODELING ELECTRON MICROSCOPY RPL42A RPL41A SCL41A YNL162W N1722 RPL42B MAK18 RPL41B SCL41B YHR141C Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Cytoplasm. Present with 17490 molecules/cell in log phase SD medium. There are 2 genes for L42 in yeast. Belongs to the ribosomal protein L44e family. Removed 1 1 60S ribosomal protein L42 2 106 N6-methyllysine 40 40 N6-methyllysine 55 55 Confers resistance to cycloheximide, an inhibitor of polypeptide elongation. Q 56 56 RK 40 41 88 89 EMBL EMBL EMBL EMBL Sequence problems. EMBL PIR C43301 PIR RefSeq RefSeq PDB 1=2-92 PDB 11.70 Z=2-106 Ensembl Saccharomyces cerevisiae Ensembl Saccharomyces cerevisiae GeneID GeneID GenomeReviews YHR141C GenomeReviews YNL162W KEGG KEGG CYGD CYGD SGD RPL42A SGD RPL42B LinkHub GermOnline Saccharomyces cerevisiae GermOnline Saccharomyces cerevisiae InterPro Ribosomal_L44E Gene3D Ribosomal_L44E 1 Pfam Ribosomal_L44 1 ProDom Ribosomal_L44E 1 PROSITE RIBOSOMAL_L44E 1 SGD SGD SGD 2007-01-23 3 12212 MVNVPKTRKT YCKGKTCRKH TQHKVTQYKA GKASLFAQGK RRYDRKQSGF GGQTKPVFHK KAKTTKKVVL RLECVKCKTR AQLTLKRCKH FELGGEKKQK GQALQF